Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes
Thrombocytopenia is a known potential side effect of hemodialysis, however, it is rarely seen in patients who undergo hemodialysis using biocompatible membranes. This case demonstrates hemodialysis-associated thrombocytopenia with use of biocompatible dialysis membranes that expose blood directly to...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/358024 |
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| _version_ | 1832567978626908160 |
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| author | Kathryn B. Muir Clifford D. Packer |
| author_facet | Kathryn B. Muir Clifford D. Packer |
| author_sort | Kathryn B. Muir |
| collection | DOAJ |
| description | Thrombocytopenia is a known potential side effect of hemodialysis, however, it is rarely seen in patients who undergo hemodialysis using biocompatible membranes. This case demonstrates hemodialysis-associated thrombocytopenia with use of biocompatible dialysis membranes that expose blood directly to polysulfone. The thrombocytopenia resolved in this patient when the dialysis membrane was changed to a biocompatible model with a polyethylene glycol barrier layer preventing direct interaction between patient blood and polysulfone. The calculated Naranjo ADR score of 9 indicates a highly probable adverse reaction. |
| format | Article |
| id | doaj-art-f2e9907ea8cc4b7f9a95f6b43f063ba3 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-f2e9907ea8cc4b7f9a95f6b43f063ba32025-02-03T01:00:02ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/358024358024Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible MembranesKathryn B. Muir0Clifford D. Packer1School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USASchool of Medicine, Case Western Reserve University, Cleveland, OH 44106, USAThrombocytopenia is a known potential side effect of hemodialysis, however, it is rarely seen in patients who undergo hemodialysis using biocompatible membranes. This case demonstrates hemodialysis-associated thrombocytopenia with use of biocompatible dialysis membranes that expose blood directly to polysulfone. The thrombocytopenia resolved in this patient when the dialysis membrane was changed to a biocompatible model with a polyethylene glycol barrier layer preventing direct interaction between patient blood and polysulfone. The calculated Naranjo ADR score of 9 indicates a highly probable adverse reaction.http://dx.doi.org/10.1155/2012/358024 |
| spellingShingle | Kathryn B. Muir Clifford D. Packer Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes Case Reports in Medicine |
| title | Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes |
| title_full | Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes |
| title_fullStr | Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes |
| title_full_unstemmed | Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes |
| title_short | Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes |
| title_sort | thrombocytopenia in the setting of hemodialysis using biocompatible membranes |
| url | http://dx.doi.org/10.1155/2012/358024 |
| work_keys_str_mv | AT kathrynbmuir thrombocytopeniainthesettingofhemodialysisusingbiocompatiblemembranes AT clifforddpacker thrombocytopeniainthesettingofhemodialysisusingbiocompatiblemembranes |