Dynamic properties of enhancer and promoter during DNA damage in hepatocellular carcinoma

Dynamic properties of enhancer and promoter during DNA damage in hepatocellular carcinoma

Summary: DNA damage is a critical factor contributing to tumorigenesis, however, the dynamic changes in multi-omics signatures of enhancers and promoters during the DNA damage response (DDR) remain poorly understood. In this study, we discovered that the expression levels, chromatin accessibility, a...

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Bibliographic Details
Main Authors: Jinyuan Zhang, Tianyu Ma, Longjun Xian, Zhiyun Guo
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
Subjects:
Molecular biology
Cancer
Genomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225008260
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