Reproductive Aging Drives Protein Accumulation in the Uterus and Limits Lifespan in C. elegans.

Reproductive Aging Drives Protein Accumulation in the Uterus and Limits Lifespan in C. elegans.

Aging in Caenorhabditis elegans is characterized by widespread physiological and molecular changes, but the mechanisms that determine the rate at which these changes occur are not well understood. In this study, we identify a novel link between reproductive aging and somatic aging in C. elegans. By...

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Bibliographic Details
Main Authors: Stephanie M Zimmerman, Izumi V Hinkson, Joshua E Elias, Stuart K Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005725&type=printable
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