Extracellular cold-inducible RNA-binding protein in CNS injury: molecular insights and therapeutic approaches

Extracellular cold-inducible RNA-binding protein in CNS injury: molecular insights and therapeutic approaches

Abstract Central nervous system (CNS) injuries, such as ischemic stroke (IS), intracerebral hemorrhage (ICH) and traumatic brain injury (TBI), are a significant global burden. The complex pathophysiology of CNS injury is comprised of primary and secondary injury. Inflammatory secondary injury is inc...

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Bibliographic Details
Main Authors: Dmitriy Lapin, Archna Sharma, Ping Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Neuroinflammation
Subjects:
CNS injury
Traumatic brain injury
Ischemic stroke
Intracerebral hemorrhage
Neuronal death
DAMPs
Online Access:https://doi.org/10.1186/s12974-025-03340-7
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