Exploring the anticancer potential of Costus speciosus: a comprehensive review

Abstract Costus speciosus is a medicinal plant with a long history in Indian Ayurvedic medicine, recognized for its diverse bioactive properties, including antibacterial, anticancer, anti-inflammatory, and antidiabetic effects. This review highlights its therapeutic potential, particularly in cancer...

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Main Authors: I. S. Al-Dhuayan, M. M. Alnamshan, A. I. Alqosaibi, R. ElMazoudy, A. A. Al-Eidan, F. M. Alkhulaifi, N. F. AlAhmady, N. A. Alenezi, M. M. Almustafa, S. S. Al-Dossari
Format: Article
Language:English
Published: Instituto Internacional de Ecologia 2025-05-01
Series:Brazilian Journal of Biology
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842025000101001&lng=en&tlng=en
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author I. S. Al-Dhuayan
M. M. Alnamshan
A. I. Alqosaibi
R. ElMazoudy
A. A. Al-Eidan
F. M. Alkhulaifi
N. F. AlAhmady
N. A. Alenezi
M. M. Almustafa
S. S. Al-Dossari
author_facet I. S. Al-Dhuayan
M. M. Alnamshan
A. I. Alqosaibi
R. ElMazoudy
A. A. Al-Eidan
F. M. Alkhulaifi
N. F. AlAhmady
N. A. Alenezi
M. M. Almustafa
S. S. Al-Dossari
author_sort I. S. Al-Dhuayan
collection DOAJ
description Abstract Costus speciosus is a medicinal plant with a long history in Indian Ayurvedic medicine, recognized for its diverse bioactive properties, including antibacterial, anticancer, anti-inflammatory, and antidiabetic effects. This review highlights its therapeutic potential, particularly in cancer treatment, where its bioactive compounds exhibit cytotoxic effects against breast, ovarian, and uterine cancers. These compounds have shown the ability to induce apoptosis, regulate the cell cycle, and inhibit cancer progression, offering a promising alternative to conventional chemotherapy with potentially fewer side effects. Additionally, C. speciosus demonstrates antioxidant, antimicrobial, and antidiabetic properties, expanding its clinical applications. Despite its promising pharmacological profile, further research is required to understand the molecular mechanisms underlying its therapeutic effects and ensure the safety and efficacy of its various extracts for therapeutic use.
format Article
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language English
publishDate 2025-05-01
publisher Instituto Internacional de Ecologia
record_format Article
series Brazilian Journal of Biology
spelling doaj-art-f2c17fa39e2b445da5a06334328d11d12025-08-20T03:14:29ZengInstituto Internacional de EcologiaBrazilian Journal of Biology1678-43752025-05-018510.1590/1519-6984.294310Exploring the anticancer potential of Costus speciosus: a comprehensive reviewI. S. Al-Dhuayanhttps://orcid.org/0000-0001-6910-0534M. M. Alnamshanhttps://orcid.org/0000-0002-9277-3996A. I. Alqosaibihttps://orcid.org/0000-0001-8348-9451R. ElMazoudyhttps://orcid.org/0000-0002-4704-7741A. A. Al-Eidanhttps://orcid.org/0000-0001-9051-9639F. M. Alkhulaifihttps://orcid.org/0000-0003-2213-7174N. F. AlAhmadyhttps://orcid.org/0000-0002-6203-2070N. A. Alenezihttps://orcid.org/0000-0002-5206-5207M. M. Almustafahttps://orcid.org/0000-0003-2853-6459S. S. Al-DossariAbstract Costus speciosus is a medicinal plant with a long history in Indian Ayurvedic medicine, recognized for its diverse bioactive properties, including antibacterial, anticancer, anti-inflammatory, and antidiabetic effects. This review highlights its therapeutic potential, particularly in cancer treatment, where its bioactive compounds exhibit cytotoxic effects against breast, ovarian, and uterine cancers. These compounds have shown the ability to induce apoptosis, regulate the cell cycle, and inhibit cancer progression, offering a promising alternative to conventional chemotherapy with potentially fewer side effects. Additionally, C. speciosus demonstrates antioxidant, antimicrobial, and antidiabetic properties, expanding its clinical applications. Despite its promising pharmacological profile, further research is required to understand the molecular mechanisms underlying its therapeutic effects and ensure the safety and efficacy of its various extracts for therapeutic use.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842025000101001&lng=en&tlng=enCostus speciousanticancerantioxidantantimicrobialantidiabeticanti-inflammatorytherapeutic medications
spellingShingle I. S. Al-Dhuayan
M. M. Alnamshan
A. I. Alqosaibi
R. ElMazoudy
A. A. Al-Eidan
F. M. Alkhulaifi
N. F. AlAhmady
N. A. Alenezi
M. M. Almustafa
S. S. Al-Dossari
Exploring the anticancer potential of Costus speciosus: a comprehensive review
Brazilian Journal of Biology
Costus specious
anticancer
antioxidant
antimicrobial
antidiabetic
anti-inflammatory
therapeutic medications
title Exploring the anticancer potential of Costus speciosus: a comprehensive review
title_full Exploring the anticancer potential of Costus speciosus: a comprehensive review
title_fullStr Exploring the anticancer potential of Costus speciosus: a comprehensive review
title_full_unstemmed Exploring the anticancer potential of Costus speciosus: a comprehensive review
title_short Exploring the anticancer potential of Costus speciosus: a comprehensive review
title_sort exploring the anticancer potential of costus speciosus a comprehensive review
topic Costus specious
anticancer
antioxidant
antimicrobial
antidiabetic
anti-inflammatory
therapeutic medications
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842025000101001&lng=en&tlng=en
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