Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report

Secondary trigeminal neuralgia (TN) is a rare manifestation of neuropathic pain in post-stroke patients, which is characterized by paroxysmal unilateral pain in the trigeminal nerve distribution, especially in strokes that occur in the brainstem. We present a case of a female patient, 28 years old,...

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Main Authors: I Gusti Agung Ayu Andra Yusari, Ida Ayu Sri Wijayanti, Ketut Widyastuti, I Made Oka Adnyana
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Bali Journal of Anesthesiology
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Online Access:https://doi.org/10.4103/bjoa.bjoa_196_24
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author I Gusti Agung Ayu Andra Yusari
Ida Ayu Sri Wijayanti
Ketut Widyastuti
I Made Oka Adnyana
author_facet I Gusti Agung Ayu Andra Yusari
Ida Ayu Sri Wijayanti
Ketut Widyastuti
I Made Oka Adnyana
author_sort I Gusti Agung Ayu Andra Yusari
collection DOAJ
description Secondary trigeminal neuralgia (TN) is a rare manifestation of neuropathic pain in post-stroke patients, which is characterized by paroxysmal unilateral pain in the trigeminal nerve distribution, especially in strokes that occur in the brainstem. We present a case of a female patient, 28 years old, with attacks of right-sided severe pain in the face, which felt like burning and electric shock. The pain began after hospitalization due to a brainstem hemorrhagic stroke in the right pons and mesencephalon, and the pain persisted for several months. She was diagnosed with secondary TN associated with brainstem hemorrhagic stroke. She experienced severe adverse reactions with the first-line pharmacological therapy, carbamazepine and gabapentin. Fluoxetine was given as an alternative therapy, and the patient began to experience improvement in the pain intensity and frequency within a few weeks. Secondary TN is a complication of hemorrhagic stroke in the brainstem, the site of the trigeminal nerve somatosensory component. Management of secondary TN after stroke has its own challenges in selecting the best medication to achieve remission of symptoms, especially when there is an adverse reaction to the first-line treatments, in this case to anticonvulsants. Antidepressants, such as fluoxetine, can be the treatment of choice to improve the symptoms of TN patients in such cases.
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institution Kabale University
issn 2549-2276
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publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
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series Bali Journal of Anesthesiology
spelling doaj-art-f2bfc403baec44a89b0684a5b6e2ada32025-01-17T10:42:56ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762024-12-018425125510.4103/bjoa.bjoa_196_24Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case ReportI Gusti Agung Ayu Andra YusariIda Ayu Sri WijayantiKetut WidyastutiI Made Oka AdnyanaSecondary trigeminal neuralgia (TN) is a rare manifestation of neuropathic pain in post-stroke patients, which is characterized by paroxysmal unilateral pain in the trigeminal nerve distribution, especially in strokes that occur in the brainstem. We present a case of a female patient, 28 years old, with attacks of right-sided severe pain in the face, which felt like burning and electric shock. The pain began after hospitalization due to a brainstem hemorrhagic stroke in the right pons and mesencephalon, and the pain persisted for several months. She was diagnosed with secondary TN associated with brainstem hemorrhagic stroke. She experienced severe adverse reactions with the first-line pharmacological therapy, carbamazepine and gabapentin. Fluoxetine was given as an alternative therapy, and the patient began to experience improvement in the pain intensity and frequency within a few weeks. Secondary TN is a complication of hemorrhagic stroke in the brainstem, the site of the trigeminal nerve somatosensory component. Management of secondary TN after stroke has its own challenges in selecting the best medication to achieve remission of symptoms, especially when there is an adverse reaction to the first-line treatments, in this case to anticonvulsants. Antidepressants, such as fluoxetine, can be the treatment of choice to improve the symptoms of TN patients in such cases.https://doi.org/10.4103/bjoa.bjoa_196_24adverse reactionantidepressantbrainstemfluoxetinehemorrhagic stroketrigeminal neuralgia
spellingShingle I Gusti Agung Ayu Andra Yusari
Ida Ayu Sri Wijayanti
Ketut Widyastuti
I Made Oka Adnyana
Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report
Bali Journal of Anesthesiology
adverse reaction
antidepressant
brainstem
fluoxetine
hemorrhagic stroke
trigeminal neuralgia
title Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report
title_full Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report
title_fullStr Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report
title_full_unstemmed Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report
title_short Secondary Trigeminal Neuralgia after a Brainstem Hemorrhagic Stroke with Adverse Reaction to Carbamazepine: A Case Report
title_sort secondary trigeminal neuralgia after a brainstem hemorrhagic stroke with adverse reaction to carbamazepine a case report
topic adverse reaction
antidepressant
brainstem
fluoxetine
hemorrhagic stroke
trigeminal neuralgia
url https://doi.org/10.4103/bjoa.bjoa_196_24
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