Prematurely Born Children: Vaccination – Safety and Specific Immune Response

The analysis of safety and efficiency of vaccination of the children born before the term (61 children of 1 – 4 degree of prematurity) and children born in time (21 children – group of comparison). For vaccination and revaccination was used: DTP (20 and 15 children respectively), DTaP (22 and 4 chil...

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Main Authors: S. M. Kharit, S. P. Kaplina, A. A. Ruleva, I. V. Friman, N. V. Skripchenko
Format: Article
Language:Russian
Published: Numikom LLC 2015-08-01
Series:Эпидемиология и вакцинопрофилактика
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Online Access:https://www.epidemvac.ru/jour/article/view/383
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author S. M. Kharit
S. P. Kaplina
A. A. Ruleva
I. V. Friman
N. V. Skripchenko
author_facet S. M. Kharit
S. P. Kaplina
A. A. Ruleva
I. V. Friman
N. V. Skripchenko
author_sort S. M. Kharit
collection DOAJ
description The analysis of safety and efficiency of vaccination of the children born before the term (61 children of 1 – 4 degree of prematurity) and children born in time (21 children – group of comparison). For vaccination and revaccination was used: DTP (20 and 15 children respectively), DTaP (22 and 4 children), pentavalentny vaccine (DTaP/IPV/Hib – 9 and 2 children) and DT (10 children of the studied group with convulsion in the anamnesis). Against measles, mumps and a rubella was immunized 47 and 20 children respectively. After immunization all clinical symptoms was analyzed and after 2 months diphtheria measles and mumps antibodies was detected.Prematurely born children has the 1 vaccination for 3 – 4 months later, then infants, with born at time. After vaccination 75.4% and 74.5% infants in both groups hadn’t any clinical symptoms. Acute respiratory infection was registered with the same frequency (25,5 – 25.0% and 24.6 – 23.8%). The antibodies titer to diphtheria, measles, mumps didn't depend on degree of prematurity.
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institution Kabale University
issn 2073-3046
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language Russian
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publisher Numikom LLC
record_format Article
series Эпидемиология и вакцинопрофилактика
spelling doaj-art-f2be8ebc5d6540c3bf3ef0b628fb862e2025-08-20T03:34:44ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942015-08-01144616610.31631/2073-3046-2015-14-4-61-66382Prematurely Born Children: Vaccination – Safety and Specific Immune ResponseS. M. Kharit0S. P. Kaplina1A. A. Ruleva2I. V. Friman3N. V. Skripchenko4Federal Medical and Biological Agency of Russia Federal State Budgetary Institution Scientific Research Institute of Children's Infections Research Institute for Childhood Infection of the Federal Medical Biological Agency of Russia; State Budgetary Educational Institution of Higher Professional Training State Budget Institution of HIgher Professional Education «St. Petersburg State Pediatric Medical University» of the Ministry of Healthcare of the Russian FederationFederal Medical and Biological Agency of Russia Federal State Budgetary Institution Scientific Research Institute of Children's Infections Research Institute for Childhood Infection of the Federal Medical Biological Agency of RussiaState Budgetary Educational Institution of Higher Professional Training State Budget Institution of HIgher Professional Education «St. Petersburg State Pediatric Medical University» of the Ministry of Healthcare of the Russian FederationFederal Medical and Biological Agency of Russia Federal State Budgetary Institution Scientific Research Institute of Children's Infections Research Institute for Childhood Infection of the Federal Medical Biological Agency of RussiaFederal Medical and Biological Agency of Russia Federal State Budgetary Institution Scientific Research Institute of Children's Infections Research Institute for Childhood Infection of the Federal Medical Biological Agency of RussiaThe analysis of safety and efficiency of vaccination of the children born before the term (61 children of 1 – 4 degree of prematurity) and children born in time (21 children – group of comparison). For vaccination and revaccination was used: DTP (20 and 15 children respectively), DTaP (22 and 4 children), pentavalentny vaccine (DTaP/IPV/Hib – 9 and 2 children) and DT (10 children of the studied group with convulsion in the anamnesis). Against measles, mumps and a rubella was immunized 47 and 20 children respectively. After immunization all clinical symptoms was analyzed and after 2 months diphtheria measles and mumps antibodies was detected.Prematurely born children has the 1 vaccination for 3 – 4 months later, then infants, with born at time. After vaccination 75.4% and 74.5% infants in both groups hadn’t any clinical symptoms. Acute respiratory infection was registered with the same frequency (25,5 – 25.0% and 24.6 – 23.8%). The antibodies titer to diphtheria, measles, mumps didn't depend on degree of prematurity.https://www.epidemvac.ru/jour/article/view/383prematurely born babyvaccination against pertussisdiphtheriatetanusmeaslesmumpsrubelladiphtheriticmeaslesmumps antibodies
spellingShingle S. M. Kharit
S. P. Kaplina
A. A. Ruleva
I. V. Friman
N. V. Skripchenko
Prematurely Born Children: Vaccination – Safety and Specific Immune Response
Эпидемиология и вакцинопрофилактика
prematurely born baby
vaccination against pertussis
diphtheria
tetanus
measles
mumps
rubella
diphtheritic
measles
mumps antibodies
title Prematurely Born Children: Vaccination – Safety and Specific Immune Response
title_full Prematurely Born Children: Vaccination – Safety and Specific Immune Response
title_fullStr Prematurely Born Children: Vaccination – Safety and Specific Immune Response
title_full_unstemmed Prematurely Born Children: Vaccination – Safety and Specific Immune Response
title_short Prematurely Born Children: Vaccination – Safety and Specific Immune Response
title_sort prematurely born children vaccination safety and specific immune response
topic prematurely born baby
vaccination against pertussis
diphtheria
tetanus
measles
mumps
rubella
diphtheritic
measles
mumps antibodies
url https://www.epidemvac.ru/jour/article/view/383
work_keys_str_mv AT smkharit prematurelybornchildrenvaccinationsafetyandspecificimmuneresponse
AT spkaplina prematurelybornchildrenvaccinationsafetyandspecificimmuneresponse
AT aaruleva prematurelybornchildrenvaccinationsafetyandspecificimmuneresponse
AT ivfriman prematurelybornchildrenvaccinationsafetyandspecificimmuneresponse
AT nvskripchenko prematurelybornchildrenvaccinationsafetyandspecificimmuneresponse