The Emerging Perspective of Morphine Tolerance: MicroRNAs

Morphine has unfavorable side effects including analgesic tolerance. Morphine tolerance counteracts analgesic efficacy and drives dose escalation. The mechanisms underlying morphine tolerance remain disputed, which has prevented the development of therapies to maximize and sustain analgesic efficacy...

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Bibliographic Details
Main Authors: Teng J. Zhang, Yong Qiu, Zhen Hua
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2019/9432965
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