Role of Hippo/ACSL4 axis in ferroptosis-induced pericyte loss and vascular dysfunction in sepsis

Role of Hippo/ACSL4 axis in ferroptosis-induced pericyte loss and vascular dysfunction in sepsis

Sepsis is a critical condition characterized by a systemic inflammatory response to infection, often leading to severe vascular dysfunction and high mortality. One of the hallmarks of vascular dysfunction in sepsis is increased vascular permeability and the loss of pericytes, which are essential for...

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Bibliographic Details
Main Authors: Yiyan Liu, Daiqin Bao, Han She, Zisen Zhang, Shifeng Shao, Zhengbin Wu, Yue Wu, Qinghui Li, Li Wang, Tao Li, Liangming Liu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Redox Biology
Subjects:
Sepsis
Ferroptosis
Pericyte loss
ACSL4
Vascular permeability
Hippo pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724003318
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