Endothelial tip-cell position, filopodia formation and biomechanics require BMPR2 expression and signaling
Abstract Blood vessel formation relies on biochemical and mechanical signals, particularly during sprouting angiogenesis when endothelial tip cells (TCs) guide sprouting through filopodia formation. The contribution of BMP receptors in defining tip-cell characteristics is poorly understood. Our stud...
Saved in:
Main Authors: | Christian Hiepen, Mounir Benamar, Jorge Barrasa-Fano, Mar Condor, Mustafa Ilhan, Juliane Münch, Nurcan Hastar, Yannic Kerkhoff, Gregory S. Harms, Thorsten Mielke, Benjamin Koenig, Stephan Block, Oliver Rocks, Salim Abdelilah-Seyfried, Hans Van Oosterwyck, Petra Knaus |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-07431-8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Contribution of Filopodia to Cell Migration: A Mechanical Link between Protrusion and Contraction
by: Fei Xue, et al.
Published: (2010-01-01) -
Hydrolyzed Collagen from Salmon Skin Increases the Migration and Filopodia Formation of Skin Keratinocytes by Activation of FAK/Src Pathway
by: Wanwipha Woonnoi, et al.
Published: (2021-09-01) -
华人遗传性混合息肉病综合征 BMPR1A 基因种系突变检测
Published: (2005-01-01) -
Effect of Bone Morphogenetic Protein Receptor-1B (BMPR-1B) Gene Variant on Litter Size in Akkaraman Sheep Breed
by: Recai Acı, et al.
Published: (2024-10-01) -
Synaptic plasticity in fronto-insular circuits underlying stress susceptibility and resilience
by: Devin Rocks, et al.
Published: (2025-02-01)