Discovery of Novel Small-Molecule Immunomodulators for Cancer Immunotherapy Using OB2C Technology
<b>Background/Objective:</b> Immunomodulators play a critical role in regulating immune responses, with immunostimulatory agents enhancing cancer therapy by activating immune cells such as T cells. While immune checkpoint inhibitors (ICIs) targeting PD-1 and CTLA-4 have shown clinical su...
Saved in:
| Main Authors: | Hsiao-Chi Wang, Tsung-Chieh Shih |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-02-01
|
| Series: | Journal of Molecular Pathology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-5261/6/1/4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeted protein degradation with small molecules for cancer immunotherapy
by: Zichao Yang, et al.
Published: (2025-08-01) -
Immunomodulatory effects of Eimeria maxima surface antigen (EmSAG) as an IFN-γ inhibitory molecule on peripheral blood mononuclear cells (PBMCs) and T cell subsets in chickens
by: Xianglin Pu, et al.
Published: (2025-05-01) -
Temperature-related intensity change (TRIC)-based high-throughput screening enables the discovery of small molecule CD28 binders
by: Laura Calvo-Barreiro, et al.
Published: (2025-09-01) -
Indoleamine 2,3-dioxygenase 1 in cancer immunotherapy: from small-molecule inhibition to PROTAC-mediated degradation
by: Xiuyun Li, et al.
Published: (2025-08-01) -
Practical Application and Influence of “Avigen duck” Immunomodulator to White Pekin Ducks Humoral Immune Factors
by: Tsvetoslav KOYNARSKI, et al.
Published: (2023-03-01)