Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope

Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope

The design of immunogens susceptible to elicit potent and broadly neutralizing antibodies against the human immunodeficiency virus type 1 (HIV-1) remains a veritable challenge in the course of vaccine development. Viral envelope proteins adopt different conformational states during the entry process...

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Bibliographic Details
Main Authors: Karim Dorgham, Nicolas Pietrancosta, Amel Affoune, Olivier Lucar, Tahar Bouceba, Solenne Chardonnet, Cedric Pionneau, Christophe Piesse, Delphine Sterlin, Pablo Guardado-Calvo, Philippe Karoyan, Patrice Debré, Guy Gorochov, Vincent Vieillard
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/9804584
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