Uptake of Risk‐Reducing Salpingo‐Oophorectomy and Gynaecologic Surveillance Among Germline BRCA Pathogenic Variants Carriers

Uptake of Risk‐Reducing Salpingo‐Oophorectomy and Gynaecologic Surveillance Among Germline BRCA Pathogenic Variants Carriers

ABSTRACT Introduction Risk‐reducing salpingo‐oophorectomy (RRSO) is recommended by international guidelines in women with BRCA1/2 germline pathogenic variants (PV) to prevent ovarian cancer. Despite the solid recommendation, women frequently refuse surgery and uptake rates reported in the literature...

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Main Authors: Alessandra Inzoli, Serena Negri, Cristina Dell'Oro, Clarissa Costa, Liliana Marchetta, Mariaclara Boccadutri, Simona Fumagalli, Gaia Roversi, Elena Maria Sala, Chiara Celi, Valentina Rossi, Robert Fruscio
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Cancer Medicine
Subjects:
BRCA mutation
cancer prevention
psychosocial studies
women's cancer
Online Access:https://doi.org/10.1002/cam4.70321
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