Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic Stresses

Plants face many abiotic stresses throughout their life cycle, such as drought, high temperature, low temperature, and salinity. To survive and reproduce, plants have evolved a complex and elaborate signal transduction network to sense stress signals and initiate corresponding defense mechanisms. Ca...

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Main Authors: Yayu Liu, Yali Qiao, Weibiao Liao
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Plants
Subjects:
Online Access:https://www.mdpi.com/2223-7747/14/4/532
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author Yayu Liu
Yali Qiao
Weibiao Liao
author_facet Yayu Liu
Yali Qiao
Weibiao Liao
author_sort Yayu Liu
collection DOAJ
description Plants face many abiotic stresses throughout their life cycle, such as drought, high temperature, low temperature, and salinity. To survive and reproduce, plants have evolved a complex and elaborate signal transduction network to sense stress signals and initiate corresponding defense mechanisms. Calcium ion (Ca<sup>2+</sup>), as a secondary messenger, plays an important role in mediating signal transduction in plant cells. Calmodulin (CaM) is an important class of Ca<sup>2+</sup> receptors that sense changes in cellular calcium ion concentration and can interact with a range of proteins to regulate the activity of downstream target proteins. Calmodulin-binding transcription factors (CAMTAs) are a family of transcription factors (TFs) that are widely present in plants and can bind to CaM. The CAMTAs are regarded as the most characterized CaM-binding TF family in the plant Ca<sup>2+</sup> signaling pathway. In recent years, studies have shown that CAMTAs play an important regulatory role in plant abiotic stress response and plant growth and development. Therefore, this review summarizes the recent progress in the discovery, structure, and role of CAMTAs under abiotic stresses, with a view to providing a reference for future CAMTA studies. Finally, the prospects and directions for further research on the potential mechanisms of CAMTAs in plants are also discussed.
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spelling doaj-art-f256d5ca90544ea69712ecaa609fae8a2025-08-20T02:44:47ZengMDPI AGPlants2223-77472025-02-0114453210.3390/plants14040532Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic StressesYayu Liu0Yali Qiao1Weibiao Liao2College of Horticulture, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Horticulture, Gansu Agricultural University, Lanzhou 730070, ChinaCollege of Horticulture, Gansu Agricultural University, Lanzhou 730070, ChinaPlants face many abiotic stresses throughout their life cycle, such as drought, high temperature, low temperature, and salinity. To survive and reproduce, plants have evolved a complex and elaborate signal transduction network to sense stress signals and initiate corresponding defense mechanisms. Calcium ion (Ca<sup>2+</sup>), as a secondary messenger, plays an important role in mediating signal transduction in plant cells. Calmodulin (CaM) is an important class of Ca<sup>2+</sup> receptors that sense changes in cellular calcium ion concentration and can interact with a range of proteins to regulate the activity of downstream target proteins. Calmodulin-binding transcription factors (CAMTAs) are a family of transcription factors (TFs) that are widely present in plants and can bind to CaM. The CAMTAs are regarded as the most characterized CaM-binding TF family in the plant Ca<sup>2+</sup> signaling pathway. In recent years, studies have shown that CAMTAs play an important regulatory role in plant abiotic stress response and plant growth and development. Therefore, this review summarizes the recent progress in the discovery, structure, and role of CAMTAs under abiotic stresses, with a view to providing a reference for future CAMTA studies. Finally, the prospects and directions for further research on the potential mechanisms of CAMTAs in plants are also discussed.https://www.mdpi.com/2223-7747/14/4/532abiotic stressCAMTAs/SRstranscription factorstranscriptional regulationstress responsesprotein interactions
spellingShingle Yayu Liu
Yali Qiao
Weibiao Liao
Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic Stresses
Plants
abiotic stress
CAMTAs/SRs
transcription factors
transcriptional regulation
stress responses
protein interactions
title Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic Stresses
title_full Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic Stresses
title_fullStr Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic Stresses
title_full_unstemmed Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic Stresses
title_short Calmodulin-Binding Transcription Factors: Roles in Plant Response to Abiotic Stresses
title_sort calmodulin binding transcription factors roles in plant response to abiotic stresses
topic abiotic stress
CAMTAs/SRs
transcription factors
transcriptional regulation
stress responses
protein interactions
url https://www.mdpi.com/2223-7747/14/4/532
work_keys_str_mv AT yayuliu calmodulinbindingtranscriptionfactorsrolesinplantresponsetoabioticstresses
AT yaliqiao calmodulinbindingtranscriptionfactorsrolesinplantresponsetoabioticstresses
AT weibiaoliao calmodulinbindingtranscriptionfactorsrolesinplantresponsetoabioticstresses