Combination of sibutramine and topiramate for the treatment of obesity: the SIBAMATE retrospective cohort study

Combination of sibutramine and topiramate for the treatment of obesity: the SIBAMATE retrospective cohort study

Abstract Background Long-term treatment of obesity with lifestyle changes alone is unsustainable for most individuals. Antiobesity medications are recommended for individuals with a body mass index (BMI) ≥ 30 kg/m² or ≥ 27 kg/m² with one or more comorbidities. In Brazil, the prescription of combined...

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Main Authors: Cintia Cercato, Matheo A. M. Stumpf, Gabriel Neimann da Cunha Freire, Eduardo Zanatta Kawahara, Ariana E. Fernandes, Maria E. de Melo, Marcio C. Mancini
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Obesity
Sibutramine
Topiramate
Antiobesity medication
Weight loss
Online Access:https://doi.org/10.1186/s13098-025-01842-1
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