Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique
Unilateral naris occlusion has long been the method of choice for effecting stimulus deprivation in studies of olfactory plasticity. A significant body of literature speaks to the myriad consequences of this manipulation on the ipsilateral olfactory pathway. Early experiments emphasized naris occlus...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2012/351752 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832562713818038272 |
|---|---|
| author | David M. Coppola |
| author_facet | David M. Coppola |
| author_sort | David M. Coppola |
| collection | DOAJ |
| description | Unilateral naris occlusion has long been the method of choice for effecting stimulus deprivation in studies of olfactory plasticity. A significant body of literature speaks to the myriad consequences of this manipulation on the ipsilateral olfactory pathway. Early experiments emphasized naris occlusion’s deleterious and age-critical effects. More recent studies have focused on life-long vulnerability, particularly on neurogenesis, and compensatory responses to deprivation. Despite the abundance of empirical data, a theoretical framework in which to understand the many sequelae of naris occlusion on olfaction has been elusive. This paper focuses on recent data, new theories, and underappreciated caveats related to the use of this technique in studies of olfactory plasticity. |
| format | Article |
| id | doaj-art-f236c31dd1d944f39a1993413f3c987b |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-f236c31dd1d944f39a1993413f3c987b2025-02-03T01:22:04ZengWileyNeural Plasticity2090-59041687-54432012-01-01201210.1155/2012/351752351752Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion TechniqueDavid M. Coppola0Department of Biology, Randolph Macon College, Ashland, VA 23005, USAUnilateral naris occlusion has long been the method of choice for effecting stimulus deprivation in studies of olfactory plasticity. A significant body of literature speaks to the myriad consequences of this manipulation on the ipsilateral olfactory pathway. Early experiments emphasized naris occlusion’s deleterious and age-critical effects. More recent studies have focused on life-long vulnerability, particularly on neurogenesis, and compensatory responses to deprivation. Despite the abundance of empirical data, a theoretical framework in which to understand the many sequelae of naris occlusion on olfaction has been elusive. This paper focuses on recent data, new theories, and underappreciated caveats related to the use of this technique in studies of olfactory plasticity.http://dx.doi.org/10.1155/2012/351752 |
| spellingShingle | David M. Coppola Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique Neural Plasticity |
| title | Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique |
| title_full | Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique |
| title_fullStr | Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique |
| title_full_unstemmed | Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique |
| title_short | Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique |
| title_sort | studies of olfactory system neural plasticity the contribution of the unilateral naris occlusion technique |
| url | http://dx.doi.org/10.1155/2012/351752 |
| work_keys_str_mv | AT davidmcoppola studiesofolfactorysystemneuralplasticitythecontributionoftheunilateralnarisocclusiontechnique |