Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature Review
Pericarditis/pericardial effusion (PC/PEEF) is a rare but fatal complication of cytosine arabinoside (Ara-C). We report an acute myeloid leukemia (AML) patient who developed massive pericardial effusion after a second Ara-C exposure. As Ara-C was most beneficial in controlling the leukemia, she was...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/4726451 |
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| _version_ | 1832568327500726272 |
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| author | Weerapat Owattanapanich Theera Ruchutrakool |
| author_facet | Weerapat Owattanapanich Theera Ruchutrakool |
| author_sort | Weerapat Owattanapanich |
| collection | DOAJ |
| description | Pericarditis/pericardial effusion (PC/PEEF) is a rare but fatal complication of cytosine arabinoside (Ara-C). We report an acute myeloid leukemia (AML) patient who developed massive pericardial effusion after a second Ara-C exposure. As Ara-C was most beneficial in controlling the leukemia, she was treated with a further cycle of Ara-C along with dexamethasone to prevent the complication from reoccurring. No PC/PEEF was subsequently detected. |
| format | Article |
| id | doaj-art-f232fde508ab4495ac1c5396aceda772 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-f232fde508ab4495ac1c5396aceda7722025-02-03T00:59:25ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/47264514726451Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature ReviewWeerapat Owattanapanich0Theera Ruchutrakool1Division of Hematology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, ThailandDivision of Hematology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, ThailandPericarditis/pericardial effusion (PC/PEEF) is a rare but fatal complication of cytosine arabinoside (Ara-C). We report an acute myeloid leukemia (AML) patient who developed massive pericardial effusion after a second Ara-C exposure. As Ara-C was most beneficial in controlling the leukemia, she was treated with a further cycle of Ara-C along with dexamethasone to prevent the complication from reoccurring. No PC/PEEF was subsequently detected.http://dx.doi.org/10.1155/2018/4726451 |
| spellingShingle | Weerapat Owattanapanich Theera Ruchutrakool Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature Review Case Reports in Hematology |
| title | Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature Review |
| title_full | Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature Review |
| title_fullStr | Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature Review |
| title_full_unstemmed | Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature Review |
| title_short | Prevention of High-Dose Cytosine Arabinoside-Induced Acute Pericarditis with Preemptive Dexamethasone Administration: A Case Report and Literature Review |
| title_sort | prevention of high dose cytosine arabinoside induced acute pericarditis with preemptive dexamethasone administration a case report and literature review |
| url | http://dx.doi.org/10.1155/2018/4726451 |
| work_keys_str_mv | AT weerapatowattanapanich preventionofhighdosecytosinearabinosideinducedacutepericarditiswithpreemptivedexamethasoneadministrationacasereportandliteraturereview AT theeraruchutrakool preventionofhighdosecytosinearabinosideinducedacutepericarditiswithpreemptivedexamethasoneadministrationacasereportandliteraturereview |