Unusual metastasis of esophageal cancer

Introduction. Carcinoma of the esophagus is in the eighth place by the frequency of malignant diseases and the sixth cause of death from cancer worldwide. It usually metastasizes to regional lymph nodes, liver, lungs, central nervous system, and bones, but metastases can appear to unusual...

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Main Authors: Vidović Vladimir, Nikolić Ivan, Vukojević Jelena, Samardžija Golub, Kukić Biljana, Bogdanović Bogdan, Petrović Nemanja
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2014-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501410975V.pdf
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author Vidović Vladimir
Nikolić Ivan
Vukojević Jelena
Samardžija Golub
Kukić Biljana
Bogdanović Bogdan
Petrović Nemanja
author_facet Vidović Vladimir
Nikolić Ivan
Vukojević Jelena
Samardžija Golub
Kukić Biljana
Bogdanović Bogdan
Petrović Nemanja
author_sort Vidović Vladimir
collection DOAJ
description Introduction. Carcinoma of the esophagus is in the eighth place by the frequency of malignant diseases and the sixth cause of death from cancer worldwide. It usually metastasizes to regional lymph nodes, liver, lungs, central nervous system, and bones, but metastases can appear to unusual locations such as facial skin and lips. Case report. We presented a 56- year-old man who reported to his physician because of upper lip swelling. A physical checkup of the patients also showed a lesion on the skin of the left temporal region and both lesions were biopsied. Based on the results of histopathological and immunohistochemical analyses of the samples a diagnosis of metastatic adenocarcinoma to the skin was established. Additional diagnostic procedures, including esophagogastroduodenoscopy, detected the infiltration into the distal part of esophagus, which was histopathologically confirmed as adenocarcinoma of esophagus. The results of positron emission tomography/computed tomography (PET/CT) examination showed the invasion of the disease. Because of the disease expansion, a multidisciplinary oncology team suggested chemo- and radiotherapy treatment. The patient has received 4 cycles of platinum-based chemotherapy so far. Conclusion. The physicians should always consider unusual skin lesions as the first sign of cancer spreading.
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spelling doaj-art-f22c4100ed04471f9538d447aa6fe7142025-08-20T03:25:22ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502014-01-01711097597710.2298/VSP1410975V0042-84501410975VUnusual metastasis of esophageal cancerVidović Vladimir0Nikolić Ivan1Vukojević Jelena2Samardžija Golub3Kukić Biljana4Bogdanović Bogdan5Petrović Nemanja6Oncology Institute of Vojvodina, Sremska KamenicaOncology Institute of Vojvodina, Sremska KamenicaOncology Institute of Vojvodina, Sremska KamenicaInstitute for Cardiovascular Diseases of Vojvodina, Sremska KamenicaOncology Institute of Vojvodina, Sremska KamenicaOncology Institute of Vojvodina, Sremska KamenicaOncology Institute of Vojvodina, Sremska KamenicaIntroduction. Carcinoma of the esophagus is in the eighth place by the frequency of malignant diseases and the sixth cause of death from cancer worldwide. It usually metastasizes to regional lymph nodes, liver, lungs, central nervous system, and bones, but metastases can appear to unusual locations such as facial skin and lips. Case report. We presented a 56- year-old man who reported to his physician because of upper lip swelling. A physical checkup of the patients also showed a lesion on the skin of the left temporal region and both lesions were biopsied. Based on the results of histopathological and immunohistochemical analyses of the samples a diagnosis of metastatic adenocarcinoma to the skin was established. Additional diagnostic procedures, including esophagogastroduodenoscopy, detected the infiltration into the distal part of esophagus, which was histopathologically confirmed as adenocarcinoma of esophagus. The results of positron emission tomography/computed tomography (PET/CT) examination showed the invasion of the disease. Because of the disease expansion, a multidisciplinary oncology team suggested chemo- and radiotherapy treatment. The patient has received 4 cycles of platinum-based chemotherapy so far. Conclusion. The physicians should always consider unusual skin lesions as the first sign of cancer spreading.http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501410975V.pdfesophageal neoplasmsneoplasm metastasislipdiagnosisadenocarcinomahistological techniquesimmunohistochemistry
spellingShingle Vidović Vladimir
Nikolić Ivan
Vukojević Jelena
Samardžija Golub
Kukić Biljana
Bogdanović Bogdan
Petrović Nemanja
Unusual metastasis of esophageal cancer
Vojnosanitetski Pregled
esophageal neoplasms
neoplasm metastasis
lip
diagnosis
adenocarcinoma
histological techniques
immunohistochemistry
title Unusual metastasis of esophageal cancer
title_full Unusual metastasis of esophageal cancer
title_fullStr Unusual metastasis of esophageal cancer
title_full_unstemmed Unusual metastasis of esophageal cancer
title_short Unusual metastasis of esophageal cancer
title_sort unusual metastasis of esophageal cancer
topic esophageal neoplasms
neoplasm metastasis
lip
diagnosis
adenocarcinoma
histological techniques
immunohistochemistry
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501410975V.pdf
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AT nikolicivan unusualmetastasisofesophagealcancer
AT vukojevicjelena unusualmetastasisofesophagealcancer
AT samardzijagolub unusualmetastasisofesophagealcancer
AT kukicbiljana unusualmetastasisofesophagealcancer
AT bogdanovicbogdan unusualmetastasisofesophagealcancer
AT petrovicnemanja unusualmetastasisofesophagealcancer