TOP2A as a prognostic biomarker in small cell carcinoma of the esophagus: an integrated bioinformatics and immunohistochemical study

TOP2A as a prognostic biomarker in small cell carcinoma of the esophagus: an integrated bioinformatics and immunohistochemical study

BackgroundSmall cell carcinoma of the esophagus (SCCE) is an infrequent but highly aggressive cancer with a poor prognosis. Given its low incidence, there is a lack of validated biomarkers to guide risk stratification and inform treatment decisions.MethodsWe extracted Differentially expressed genes...

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Bibliographic Details
Main Authors: Xiaolei Yin, Xiaopeng Li, Lili Mi, Jiaojiao Hou, Fei Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
TOP2A
small cell carcinoma of the esophagus
prognostic biomarker
bioinformatics
immunohistochemistry
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1640881/full
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