Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetry
Purpose: To assess the severity of glaucoma and its worsening using Spaeth/Richman contrast sensitivity (SPARCS). To evaluate its correlation with retinal nerve fiber layer thickness (RNFL) and perimetry. Methods: In this prospective observational study, 90 eyes of primary open-angle glaucoma were c...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-03-01
|
| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/IJO.IJO_2289_23 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849773014197993472 |
|---|---|
| author | Shihail Jinna Kavita R Bhatnagar Kirti Jaisingh Jyoti Shakrawal Seema Meena Nikhil Agarwal |
| author_facet | Shihail Jinna Kavita R Bhatnagar Kirti Jaisingh Jyoti Shakrawal Seema Meena Nikhil Agarwal |
| author_sort | Shihail Jinna |
| collection | DOAJ |
| description | Purpose:
To assess the severity of glaucoma and its worsening using Spaeth/Richman contrast sensitivity (SPARCS). To evaluate its correlation with retinal nerve fiber layer thickness (RNFL) and perimetry.
Methods:
In this prospective observational study, 90 eyes of primary open-angle glaucoma were categorized into mild, moderate, and severe glaucoma (30 each). All eyes were subjected to contrast sensitivity measurements by using the Pelli-Robson (PR) chart and SPARCS, Humphrey automated perimetry, and optical coherence tomography (OCT) RNFL, along with routine ophthalmological evaluation at baseline. Contrast sensitivity was repeated at 1, 3, and 6 months. Other investigations were repeated at 6 months. The correlation between contrast sensitivity and other parameters was analyzed at baseline and 6 months.
Results:
Total SPARCS showed a significant positive correlation with visual field index, pattern standard deviation, mean deviation, OCT RNFL, and a negative correlation with best corrected visual acuity. Central SPARCS and PR scores exhibited strong positive correlations. Both total and quadrantic SPARCS significantly reduced from mild to moderate to severe glaucoma. The quadrant-wise SPARCS also correlated well with opposite-side RNFL thickness. At 6 months, SPARCS showed a significant reduction along with RNFL measurements preceding any significant changes in visual field parameters.
Conclusion:
This study establishes SPARCS as a reliable and reproducible tool in assessing the deterioration of visual function in glaucoma patients even before significant perimetric changes. The specific relationship of quadrantic SPARCS with opposite-side RNFL is a novel yet expected finding. The findings advocate integrating SPARCS into routine glaucoma assessment for timely detection of any worsening and prompt intervention, improving the visual outcomes in these patients. |
| format | Article |
| id | doaj-art-f20a1d85dd2247df95bd5da613aad291 |
| institution | DOAJ |
| issn | 0301-4738 1998-3689 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj-art-f20a1d85dd2247df95bd5da613aad2912025-08-20T03:02:10ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-03-0173Suppl 2S282S28610.4103/IJO.IJO_2289_23Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetryShihail JinnaKavita R BhatnagarKirti JaisinghJyoti ShakrawalSeema MeenaNikhil AgarwalPurpose: To assess the severity of glaucoma and its worsening using Spaeth/Richman contrast sensitivity (SPARCS). To evaluate its correlation with retinal nerve fiber layer thickness (RNFL) and perimetry. Methods: In this prospective observational study, 90 eyes of primary open-angle glaucoma were categorized into mild, moderate, and severe glaucoma (30 each). All eyes were subjected to contrast sensitivity measurements by using the Pelli-Robson (PR) chart and SPARCS, Humphrey automated perimetry, and optical coherence tomography (OCT) RNFL, along with routine ophthalmological evaluation at baseline. Contrast sensitivity was repeated at 1, 3, and 6 months. Other investigations were repeated at 6 months. The correlation between contrast sensitivity and other parameters was analyzed at baseline and 6 months. Results: Total SPARCS showed a significant positive correlation with visual field index, pattern standard deviation, mean deviation, OCT RNFL, and a negative correlation with best corrected visual acuity. Central SPARCS and PR scores exhibited strong positive correlations. Both total and quadrantic SPARCS significantly reduced from mild to moderate to severe glaucoma. The quadrant-wise SPARCS also correlated well with opposite-side RNFL thickness. At 6 months, SPARCS showed a significant reduction along with RNFL measurements preceding any significant changes in visual field parameters. Conclusion: This study establishes SPARCS as a reliable and reproducible tool in assessing the deterioration of visual function in glaucoma patients even before significant perimetric changes. The specific relationship of quadrantic SPARCS with opposite-side RNFL is a novel yet expected finding. The findings advocate integrating SPARCS into routine glaucoma assessment for timely detection of any worsening and prompt intervention, improving the visual outcomes in these patients.https://journals.lww.com/10.4103/IJO.IJO_2289_23contrast sensitivityglaucomaoct rnflperimetrysparcs |
| spellingShingle | Shihail Jinna Kavita R Bhatnagar Kirti Jaisingh Jyoti Shakrawal Seema Meena Nikhil Agarwal Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetry Indian Journal of Ophthalmology contrast sensitivity glaucoma oct rnfl perimetry sparcs |
| title | Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetry |
| title_full | Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetry |
| title_fullStr | Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetry |
| title_full_unstemmed | Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetry |
| title_short | Assessment of glaucoma severity and deterioration by using Spaeth/Richman contrast sensitivity (SPARCS) and its correlation with retinal nerve fiber layer thickness and perimetry |
| title_sort | assessment of glaucoma severity and deterioration by using spaeth richman contrast sensitivity sparcs and its correlation with retinal nerve fiber layer thickness and perimetry |
| topic | contrast sensitivity glaucoma oct rnfl perimetry sparcs |
| url | https://journals.lww.com/10.4103/IJO.IJO_2289_23 |
| work_keys_str_mv | AT shihailjinna assessmentofglaucomaseverityanddeteriorationbyusingspaethrichmancontrastsensitivitysparcsanditscorrelationwithretinalnervefiberlayerthicknessandperimetry AT kavitarbhatnagar assessmentofglaucomaseverityanddeteriorationbyusingspaethrichmancontrastsensitivitysparcsanditscorrelationwithretinalnervefiberlayerthicknessandperimetry AT kirtijaisingh assessmentofglaucomaseverityanddeteriorationbyusingspaethrichmancontrastsensitivitysparcsanditscorrelationwithretinalnervefiberlayerthicknessandperimetry AT jyotishakrawal assessmentofglaucomaseverityanddeteriorationbyusingspaethrichmancontrastsensitivitysparcsanditscorrelationwithretinalnervefiberlayerthicknessandperimetry AT seemameena assessmentofglaucomaseverityanddeteriorationbyusingspaethrichmancontrastsensitivitysparcsanditscorrelationwithretinalnervefiberlayerthicknessandperimetry AT nikhilagarwal assessmentofglaucomaseverityanddeteriorationbyusingspaethrichmancontrastsensitivitysparcsanditscorrelationwithretinalnervefiberlayerthicknessandperimetry |