Influence of Age, Past Smoking, and Disease Severity on TLR2, Neutrophilic Inflammation, and MMP-9 Levels in COPD
Chronic obstructive pulmonary disease (COPD) is a common and serious respiratory disease, particularly in older individuals, characterised by fixed airway obstruction and persistent airway neutrophilia. The mechanisms that lead to these features are not well established. We investigated the contribu...
Saved in:
| Main Authors: | Jodie L. Simpson, Vanessa M. McDonald, Katherine J. Baines, Kevin M. Oreo, Fang Wang, Philip M. Hansbro, Peter G. Gibson |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2013/462934 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
TLR2, TLR4 AND MyD88 Mediate Allergic Airway Disease (AAD) and Streptococcus pneumoniae-Induced Suppression of AAD.
by: Alison N Thorburn, et al.
Published: (2016-01-01) -
Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock
by: Zheng Qiu, et al.
Published: (2014-01-01) -
Expressions of MMP-12, TIMP-4, and Neutrophil Elastase in PBMCs and Exhaled Breath Condensate in Patients with COPD and Their Relationships with Disease Severity and Acute Exacerbations
by: Wendong Hao, et al.
Published: (2019-01-01) -
MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury
by: Shiyu Hu, et al.
Published: (2025-06-01) -
Successful Smoking Cessation in COPD: Association with Comorbidities and Mortality
by: H. Kupiainen, et al.
Published: (2012-01-01)