An efficient bacterial laccase-mediated system for polyurethane foam degradation

Polyurethane (PU), a segmented block copolymer with chemically resistant urethane linkages and tunable architecture, presents persistent biological recycling challenges. This study presents a Bacterial Laccase-Mediated System (BLMS) derived from Bacillus subtilis for efficient degradation of polyest...

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Main Authors: Xiaomin Zhu, Youren Duan, Jianqi Lu, Wei Xia, Yujia Peng, Jiawei Liu, Weiliang Dong, Min Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1638208/full
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author Xiaomin Zhu
Youren Duan
Jianqi Lu
Wei Xia
Yujia Peng
Jiawei Liu
Weiliang Dong
Weiliang Dong
Min Jiang
Min Jiang
author_facet Xiaomin Zhu
Youren Duan
Jianqi Lu
Wei Xia
Yujia Peng
Jiawei Liu
Weiliang Dong
Weiliang Dong
Min Jiang
Min Jiang
author_sort Xiaomin Zhu
collection DOAJ
description Polyurethane (PU), a segmented block copolymer with chemically resistant urethane linkages and tunable architecture, presents persistent biological recycling challenges. This study presents a Bacterial Laccase-Mediated System (BLMS) derived from Bacillus subtilis for efficient degradation of polyester- and polyether-PU. Utilizing the laccase CotA and mediator 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), the BLMS demonstrated effective de polymerization of both commercial and self-synthesized PU foams, including polyester- and polyether-types. The weight loss of the self-synthesized polyester-foam and the commercial polyether-foam reached up to 21.24 ± 1.20% and 3.81 ± 0.36%, respectively. Subsequently, we detected oxygenated products such as ketones, alcohols, aldehydes, acids, esters, ethers, and 2,4– toluenediamine (2,4-TDA) indicating that bacterial laccase CotA exhibited redox catalytic activity toward PU. Moreover, an interesting phenomenon was observed during the degradation process that the solution turned purple. We predicted that this attribute to the enzymatic oxidation of ABTS to the radical cation ABTS·+, which subsequently reacts with 2,4-TDA to form the purple product. This study finds a plastic degrading enzyme capable of hydrolyzing urethane bonds in PU, offering a promising contribution to the development of a bio-based circular economy for PU biodegradation and recycling.
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publishDate 2025-08-01
publisher Frontiers Media S.A.
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spelling doaj-art-f1eb62dccfa44d9db6fa9686b4b00b372025-08-25T05:25:17ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2025-08-011610.3389/fmicb.2025.16382081638208An efficient bacterial laccase-mediated system for polyurethane foam degradationXiaomin Zhu0Youren Duan1Jianqi Lu2Wei Xia3Yujia Peng4Jiawei Liu5Weiliang Dong6Weiliang Dong7Min Jiang8Min Jiang9Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaKey Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaKey Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaKey Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaKey Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaKey Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaKey Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaState Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, ChinaKey Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, ChinaState Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, ChinaPolyurethane (PU), a segmented block copolymer with chemically resistant urethane linkages and tunable architecture, presents persistent biological recycling challenges. This study presents a Bacterial Laccase-Mediated System (BLMS) derived from Bacillus subtilis for efficient degradation of polyester- and polyether-PU. Utilizing the laccase CotA and mediator 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), the BLMS demonstrated effective de polymerization of both commercial and self-synthesized PU foams, including polyester- and polyether-types. The weight loss of the self-synthesized polyester-foam and the commercial polyether-foam reached up to 21.24 ± 1.20% and 3.81 ± 0.36%, respectively. Subsequently, we detected oxygenated products such as ketones, alcohols, aldehydes, acids, esters, ethers, and 2,4– toluenediamine (2,4-TDA) indicating that bacterial laccase CotA exhibited redox catalytic activity toward PU. Moreover, an interesting phenomenon was observed during the degradation process that the solution turned purple. We predicted that this attribute to the enzymatic oxidation of ABTS to the radical cation ABTS·+, which subsequently reacts with 2,4-TDA to form the purple product. This study finds a plastic degrading enzyme capable of hydrolyzing urethane bonds in PU, offering a promising contribution to the development of a bio-based circular economy for PU biodegradation and recycling.https://www.frontiersin.org/articles/10.3389/fmicb.2025.1638208/fullpolyurethanebacterial laccase CotAABTSdegradation mechanismcolor shift
spellingShingle Xiaomin Zhu
Youren Duan
Jianqi Lu
Wei Xia
Yujia Peng
Jiawei Liu
Weiliang Dong
Weiliang Dong
Min Jiang
Min Jiang
An efficient bacterial laccase-mediated system for polyurethane foam degradation
Frontiers in Microbiology
polyurethane
bacterial laccase CotA
ABTS
degradation mechanism
color shift
title An efficient bacterial laccase-mediated system for polyurethane foam degradation
title_full An efficient bacterial laccase-mediated system for polyurethane foam degradation
title_fullStr An efficient bacterial laccase-mediated system for polyurethane foam degradation
title_full_unstemmed An efficient bacterial laccase-mediated system for polyurethane foam degradation
title_short An efficient bacterial laccase-mediated system for polyurethane foam degradation
title_sort efficient bacterial laccase mediated system for polyurethane foam degradation
topic polyurethane
bacterial laccase CotA
ABTS
degradation mechanism
color shift
url https://www.frontiersin.org/articles/10.3389/fmicb.2025.1638208/full
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