A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein
Abstract The hepatic portal vein is the main vascular route responsible for collecting blood from the liver, spleen, pancreas, stomach, gallbladder, and intestines. Its key function is to metabolize the components acquired from the blood. The objective of this study was to analyze the characteristic...
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Nature Portfolio
2024-12-01
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| Online Access: | https://doi.org/10.1038/s41598-024-81543-3 |
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| author | Juan José Valenzuela-Fuenzalida Benjamín Rodríguez-Osorio Cristian Salgado-Torres Pablo Nova-Baeza Mathias Orellana-Donoso Alejandro Bruna-Mejías Roberto Avila-Sepulveda Álvaro Becerra-Farfán Macarena Rodríguez-Luengo Juan Sanchis-Gimeno Guinevere Granite Héctor Gutiérrez-Espinoza |
| author_facet | Juan José Valenzuela-Fuenzalida Benjamín Rodríguez-Osorio Cristian Salgado-Torres Pablo Nova-Baeza Mathias Orellana-Donoso Alejandro Bruna-Mejías Roberto Avila-Sepulveda Álvaro Becerra-Farfán Macarena Rodríguez-Luengo Juan Sanchis-Gimeno Guinevere Granite Héctor Gutiérrez-Espinoza |
| author_sort | Juan José Valenzuela-Fuenzalida |
| collection | DOAJ |
| description | Abstract The hepatic portal vein is the main vascular route responsible for collecting blood from the liver, spleen, pancreas, stomach, gallbladder, and intestines. Its key function is to metabolize the components acquired from the blood. The objective of this study was to analyze the characteristics of HPV variants and understand the possible clinical considerations that arise with them. The databases Medline, Scopus, Web of Science, Google Scholar, Cumulative Index to Nursing and Allied Health Literature and Latin American and Caribbean Literature in Health Sciences were researched until January 2024. Tree authors independently performed the search, study selection and data extraction. Methodological quality was evaluated with an assurance tool for anatomical studies. Pooled prevalence was estimated using a random effects model. A total of 31 studies met the established selection criteria. In this study, 21 articles were included for the meta-analysis with a total of 51,244 subjects. Of these 21 articles, the topics studied came mainly from Europe and Asia, with three (n = 554; 1.08%) and 11 articles (n = 50,090; 97.75%) respectively, also having six articles from North America (n = 442; 0.86%) and one from Africa (n = 158; 0.31%), discarding the articles from Oceania and South America. For the HPV trifurcation variant, it was 8% (CI = 7-10%). Apropos the right posterior portal vein variant, as the primary tributary from the main HPV, it was 7% (CI = 4-11%). About the right anterior portal vein variant originating from the left portal vein, it was 4% (CI = 1-6%). Finally, the prevalence of the isolated variants was 2% (CI = 1-3%). The knowledge of HPV and its anatomical variants is of utmost importance for both medical professionals and anatomists, as it is one of the vessels that collects blood from many important viscera found in the abdominal cavity, any structural alteration could be crucial in diagnosis and surgical procedures. |
| format | Article |
| id | doaj-art-f1e3aac50188432aa3131a9e62b60754 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-f1e3aac50188432aa3131a9e62b607542025-02-09T12:38:01ZengNature PortfolioScientific Reports2045-23222024-12-0114112310.1038/s41598-024-81543-3A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal veinJuan José Valenzuela-Fuenzalida0Benjamín Rodríguez-Osorio1Cristian Salgado-Torres2Pablo Nova-Baeza3Mathias Orellana-Donoso4Alejandro Bruna-Mejías5Roberto Avila-Sepulveda6Álvaro Becerra-Farfán7Macarena Rodríguez-Luengo8Juan Sanchis-Gimeno9Guinevere Granite10Héctor Gutiérrez-Espinoza11Departamento de Morfología, Facultad de Medicina, Universidad Andrés BelloDepartamento de Morfología, Facultad de Medicina, Universidad Andrés BelloDepartamento de Morfología, Facultad de Medicina, Universidad Andrés BelloDepartamento de Morfología, Facultad de Medicina, Universidad Andrés BelloEscuela de Medicina, Universidad Finis TerraeDepartamento de Ciencias y Geografía, Facultad de Ciencias Naturales y Exactas, Universidad de Playa AnchaDepartamento de Morfología, Facultad de Medicina, Universidad Andrés BelloDepartamento de Ciencias Química y Biológicas, Facultad de Ciencias de la Salud, Universidad Bernardo O’HigginsDepartamento de Morfología, Facultad de Medicina, Universidad Andrés BelloGIAVAL Research Group, Department of Anatomy and Human Embryology, Faculty of Medicine, University of ValenciaDepartment of Surgery, Uniformed Services University of the Health SciencesOne Health Research Group, Universidad de las AmericasAbstract The hepatic portal vein is the main vascular route responsible for collecting blood from the liver, spleen, pancreas, stomach, gallbladder, and intestines. Its key function is to metabolize the components acquired from the blood. The objective of this study was to analyze the characteristics of HPV variants and understand the possible clinical considerations that arise with them. The databases Medline, Scopus, Web of Science, Google Scholar, Cumulative Index to Nursing and Allied Health Literature and Latin American and Caribbean Literature in Health Sciences were researched until January 2024. Tree authors independently performed the search, study selection and data extraction. Methodological quality was evaluated with an assurance tool for anatomical studies. Pooled prevalence was estimated using a random effects model. A total of 31 studies met the established selection criteria. In this study, 21 articles were included for the meta-analysis with a total of 51,244 subjects. Of these 21 articles, the topics studied came mainly from Europe and Asia, with three (n = 554; 1.08%) and 11 articles (n = 50,090; 97.75%) respectively, also having six articles from North America (n = 442; 0.86%) and one from Africa (n = 158; 0.31%), discarding the articles from Oceania and South America. For the HPV trifurcation variant, it was 8% (CI = 7-10%). Apropos the right posterior portal vein variant, as the primary tributary from the main HPV, it was 7% (CI = 4-11%). About the right anterior portal vein variant originating from the left portal vein, it was 4% (CI = 1-6%). Finally, the prevalence of the isolated variants was 2% (CI = 1-3%). The knowledge of HPV and its anatomical variants is of utmost importance for both medical professionals and anatomists, as it is one of the vessels that collects blood from many important viscera found in the abdominal cavity, any structural alteration could be crucial in diagnosis and surgical procedures.https://doi.org/10.1038/s41598-024-81543-3Portal veinHepatic portal veinVariation portal veinPortal triadVariation anatomicalClinical anatomy |
| spellingShingle | Juan José Valenzuela-Fuenzalida Benjamín Rodríguez-Osorio Cristian Salgado-Torres Pablo Nova-Baeza Mathias Orellana-Donoso Alejandro Bruna-Mejías Roberto Avila-Sepulveda Álvaro Becerra-Farfán Macarena Rodríguez-Luengo Juan Sanchis-Gimeno Guinevere Granite Héctor Gutiérrez-Espinoza A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein Scientific Reports Portal vein Hepatic portal vein Variation portal vein Portal triad Variation anatomical Clinical anatomy |
| title | A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein |
| title_full | A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein |
| title_fullStr | A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein |
| title_full_unstemmed | A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein |
| title_short | A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein |
| title_sort | systematic review and meta analysis prevalence and clinical implications of anatomical variants of the hepatic portal vein |
| topic | Portal vein Hepatic portal vein Variation portal vein Portal triad Variation anatomical Clinical anatomy |
| url | https://doi.org/10.1038/s41598-024-81543-3 |
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