Diet, oxidative stress and MAFLD: a mini review
Globally, metabolic dysfunction-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), is a common chronic liver disease. The progression of MAFLD leads to a vicious cycle in which oxidative...
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Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2025.1539578/full |
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| author | Zenan Hu Zenan Hu Hanxun Yue Na Jiang Liang Qiao |
| author_facet | Zenan Hu Zenan Hu Hanxun Yue Na Jiang Liang Qiao |
| author_sort | Zenan Hu |
| collection | DOAJ |
| description | Globally, metabolic dysfunction-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), is a common chronic liver disease. The progression of MAFLD leads to a vicious cycle in which oxidative stress results from the disease that is augmenting de-novo lipid levels and increases steatosis. Most non-enzymatic antioxidants are present in food. Therefore, the present review summarizes the findings of studies on food-derived antioxidants and presents an oxidative stress-related regulatory network in MAFLD, offering new ideas for MAFLD prevention and treatment. |
| format | Article |
| id | doaj-art-f1d85d5eadda4a08a42ea88b4b4c13bd |
| institution | DOAJ |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj-art-f1d85d5eadda4a08a42ea88b4b4c13bd2025-08-20T03:00:05ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-03-011210.3389/fnut.2025.15395781539578Diet, oxidative stress and MAFLD: a mini reviewZenan Hu0Zenan Hu1Hanxun Yue2Na Jiang3Liang Qiao4The First School of Clinical Medicine, Lanzhou University, Lanzhou, ChinaDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, ChinaDepartment of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, ChinaSchool of Public Health, Lanzhou University, Lanzhou, ChinaStorr Liver Centre, Westmead Institute for Medical Research, The University of Sydney and Westmead Hospital, Westmead, NSW, AustraliaGlobally, metabolic dysfunction-associated fatty liver disease (MAFLD), also known as non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), is a common chronic liver disease. The progression of MAFLD leads to a vicious cycle in which oxidative stress results from the disease that is augmenting de-novo lipid levels and increases steatosis. Most non-enzymatic antioxidants are present in food. Therefore, the present review summarizes the findings of studies on food-derived antioxidants and presents an oxidative stress-related regulatory network in MAFLD, offering new ideas for MAFLD prevention and treatment.https://www.frontiersin.org/articles/10.3389/fnut.2025.1539578/fulldietoxidative stressMAFLDNAFLDMASLD |
| spellingShingle | Zenan Hu Zenan Hu Hanxun Yue Na Jiang Liang Qiao Diet, oxidative stress and MAFLD: a mini review Frontiers in Nutrition diet oxidative stress MAFLD NAFLD MASLD |
| title | Diet, oxidative stress and MAFLD: a mini review |
| title_full | Diet, oxidative stress and MAFLD: a mini review |
| title_fullStr | Diet, oxidative stress and MAFLD: a mini review |
| title_full_unstemmed | Diet, oxidative stress and MAFLD: a mini review |
| title_short | Diet, oxidative stress and MAFLD: a mini review |
| title_sort | diet oxidative stress and mafld a mini review |
| topic | diet oxidative stress MAFLD NAFLD MASLD |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2025.1539578/full |
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