BAFF and APRIL immunotherapy following Bacille Calmette-Guérin vaccination enhances protection against pulmonary tuberculosis in mice
IntroductionBacille Calmette-Guérin (BCG), the only tuberculosis vaccine currently in clinical use, provides inadequate long-term protection. Administered at birth, BCG induces broad immune responses against a large number of antigens shared with Mycobacterium tuberculosis (Mtb), but protection wane...
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Main Authors: | Min Xie, Chen-Yu Tsai, Joshua Woo, Frank Nuritdinov, Melissa Cristaldo, Narineh M. Odjourian, Rosleine Antilus-Sainte, Maureen Dougher, Martin Gengenbacher |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-02-01
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Series: | Frontiers in Immunology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551183/full |
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