Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer

Paraneoplastic syndrome associated with prostate cancer is extremely rare. We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutam...

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Main Authors: Tomomi Kuramoto, Hiroya Senzaki, Hiroyuki Koike, Kenji Yamagiwa, Shinobu Tamura, Tokuzou Fujimoto, Takeshi Inagaki
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2013/303727
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author Tomomi Kuramoto
Hiroya Senzaki
Hiroyuki Koike
Kenji Yamagiwa
Shinobu Tamura
Tokuzou Fujimoto
Takeshi Inagaki
author_facet Tomomi Kuramoto
Hiroya Senzaki
Hiroyuki Koike
Kenji Yamagiwa
Shinobu Tamura
Tokuzou Fujimoto
Takeshi Inagaki
author_sort Tomomi Kuramoto
collection DOAJ
description Paraneoplastic syndrome associated with prostate cancer is extremely rare. We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutamide and leuprolide, the patient’s symptoms and laboratory abnormalities were reversed. Cholestatic jaundice was regarded as a paraneoplastic manifestation in this patient. The patient remains symptom-free after 14-month followup. Paraneoplastic syndrome should be considered in case of cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection.
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publishDate 2013-01-01
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series Case Reports in Urology
spelling doaj-art-f1cb5e2f912f44de9ffec6a97671765e2025-02-03T01:23:47ZengWileyCase Reports in Urology2090-696X2090-69782013-01-01201310.1155/2013/303727303727Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate CancerTomomi Kuramoto0Hiroya Senzaki1Hiroyuki Koike2Kenji Yamagiwa3Shinobu Tamura4Tokuzou Fujimoto5Takeshi Inagaki6Department of Urology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, JapanDepartment of Urology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, JapanDepartment of Urology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, JapanDepartment of Urology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, JapanDepartment of Hematology/Oncology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, JapanDepartment of Internal Medicine, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, JapanDepartment of Urology, Social Insurance Kinan Hospital, 46-70 Shinjou-chou, Tanabe-shi, Wakayama 646-8588, JapanParaneoplastic syndrome associated with prostate cancer is extremely rare. We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutamide and leuprolide, the patient’s symptoms and laboratory abnormalities were reversed. Cholestatic jaundice was regarded as a paraneoplastic manifestation in this patient. The patient remains symptom-free after 14-month followup. Paraneoplastic syndrome should be considered in case of cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection.http://dx.doi.org/10.1155/2013/303727
spellingShingle Tomomi Kuramoto
Hiroya Senzaki
Hiroyuki Koike
Kenji Yamagiwa
Shinobu Tamura
Tokuzou Fujimoto
Takeshi Inagaki
Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer
Case Reports in Urology
title Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer
title_full Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer
title_fullStr Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer
title_full_unstemmed Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer
title_short Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer
title_sort cholestatic jaundice as a paraneoplastic manifestation of prostate cancer
url http://dx.doi.org/10.1155/2013/303727
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