Clinical Outcomes of CDK4/6 Inhibitor Therapy in HR+/HER2− Metastatic Breast Cancer: A Multicenter Comparison of HER2-Low and HER2-Zero Subgroups

Conclusion: HER2 status did not significantly impact treatment outcomes with CDK4/6i in HR+/HER2-negative MBC patients. However, subgroup analyses indicated that metastatic burden, particularly the number of metastatic sites and the presence of visceral disease, may adversely influence PFS. These fi...

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Bibliographic Details
Main Authors: Erkan Ozcan, Ivo Gokmen, Fahri Akgul, Fatma Akdag Kahvecioglu, Abdussamet Celebi, Osman Kostek, Ilhan Hacıbekiroglu, Bulent Erdogan
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:The Breast Journal
Online Access:http://dx.doi.org/10.1155/tbj/5577345
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