Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation
Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation. Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to r...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2016/4917659 |
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| author | A-Yong Yu Hua Guo Qin-Mei Wang Fang-Jun Bao Jing-Hai Huang |
| author_facet | A-Yong Yu Hua Guo Qin-Mei Wang Fang-Jun Bao Jing-Hai Huang |
| author_sort | A-Yong Yu |
| collection | DOAJ |
| description | Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation. Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to receive intracamerally 1 mL epinephrine hydrochloride 0.001% for 1 minute after corneal incision (intracameral group), and the contralateral eye received 3 drops of compound tropicamide 0.5% and phenylephrine 0.5% at 5-minute intervals 30 minutes before surgery (topical group). Pupil diameters were measured before corneal incision, before ophthalmic viscoelastic device (OVD) injection, after OVD injection, before IOL implantation, and at the end of surgery. Results. At each time point, the mean pupil diameter in the intracameral group was 2.20±0.08, 5.09±0.20, 6.76±0.19, 6.48±0.18, and 5.97±0.24 mm, respectively, and in the topical group it was 7.98±0.15, 7.98±0.15, 8.53±0.14, 8.27±0.16, and 7.93±0.20 mm, respectively. The topical group consistently had larger mydriatic effects than the intracameral group (P<0.05). The onset of mydriatic effect was rapid in the intracameral group. There was no difference in surgical performance or other parameters between groups. Conclusions. Intracameral epinephrine hydrochloride appears to be an alternative to the mydriatic modalities for phacoemulsification and IOL implantation. In comparison with topical mydriatics, intracameral epinephrine hydrochloride offers easier preoperative preparation, more rapid pupil dilation, and comparable surgical performance. |
| format | Article |
| id | doaj-art-f1bc60c75c1b4827913129762117fe7a |
| institution | DOAJ |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-f1bc60c75c1b4827913129762117fe7a2025-08-20T03:20:47ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/49176594917659Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens ImplantationA-Yong Yu0Hua Guo1Qin-Mei Wang2Fang-Jun Bao3Jing-Hai Huang4The Eye Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaThe Eye Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaThe Eye Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaThe Eye Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaThe Eye Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaObjective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation. Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to receive intracamerally 1 mL epinephrine hydrochloride 0.001% for 1 minute after corneal incision (intracameral group), and the contralateral eye received 3 drops of compound tropicamide 0.5% and phenylephrine 0.5% at 5-minute intervals 30 minutes before surgery (topical group). Pupil diameters were measured before corneal incision, before ophthalmic viscoelastic device (OVD) injection, after OVD injection, before IOL implantation, and at the end of surgery. Results. At each time point, the mean pupil diameter in the intracameral group was 2.20±0.08, 5.09±0.20, 6.76±0.19, 6.48±0.18, and 5.97±0.24 mm, respectively, and in the topical group it was 7.98±0.15, 7.98±0.15, 8.53±0.14, 8.27±0.16, and 7.93±0.20 mm, respectively. The topical group consistently had larger mydriatic effects than the intracameral group (P<0.05). The onset of mydriatic effect was rapid in the intracameral group. There was no difference in surgical performance or other parameters between groups. Conclusions. Intracameral epinephrine hydrochloride appears to be an alternative to the mydriatic modalities for phacoemulsification and IOL implantation. In comparison with topical mydriatics, intracameral epinephrine hydrochloride offers easier preoperative preparation, more rapid pupil dilation, and comparable surgical performance.http://dx.doi.org/10.1155/2016/4917659 |
| spellingShingle | A-Yong Yu Hua Guo Qin-Mei Wang Fang-Jun Bao Jing-Hai Huang Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation Journal of Ophthalmology |
| title | Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation |
| title_full | Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation |
| title_fullStr | Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation |
| title_full_unstemmed | Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation |
| title_short | Pupil Dilation with Intracameral Epinephrine Hydrochloride during Phacoemulsification and Intraocular Lens Implantation |
| title_sort | pupil dilation with intracameral epinephrine hydrochloride during phacoemulsification and intraocular lens implantation |
| url | http://dx.doi.org/10.1155/2016/4917659 |
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