Mapping lineage-traced cells across time points with moslin

Mapping lineage-traced cells across time points with moslin

Abstract Simultaneous profiling of single-cell gene expression and lineage history holds enormous potential for studying cellular decision-making. Recent computational approaches combine both modalities into cellular trajectories; however, they cannot make use of all available lineage information in...

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Bibliographic Details
Main Authors: Marius Lange, Zoe Piran, Michal Klein, Bastiaan Spanjaard, Dominik Klein, Jan Philipp Junker, Fabian J. Theis, Mor Nitzan
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Genome Biology
Subjects:
Fate decisions
Lineage tracing
Cellular dynamics
Optimal transport
Regeneration
Online Access:https://doi.org/10.1186/s13059-024-03422-4
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