Designing Adjuvant Formulations to Promote Immunogenicity and Protective Efficacy of Leptospira Immunoglobulin-Like Protein A Subunit Vaccine

Designing Adjuvant Formulations to Promote Immunogenicity and Protective Efficacy of Leptospira Immunoglobulin-Like Protein A Subunit Vaccine

The leptospirosis burden on humans, especially in high-risk occupational groups and livestock, leads to public health and economic problems. Leptospirosis subunit vaccines have been under development and require further improvement to provide complete protection. Adjuvants can be used to enhance the...

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Bibliographic Details
Main Authors: Teerasit Techawiwattanaboon, Thomas Courant, Livia Brunner, Suwitra Sathean-anan-kun, Pratomporn Krangvichian, Nutta Iadsee, Yaowarin Nakornpakdee, Noppadon Sangjun, Pat Komanee, Nicolas Collin, Kiat Ruxrungtham, Kanitha Patarakul
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Leptospira
immunoglobulin-like protein A
subunit vaccine
adjuvant formulation
neutral liposome
squalene-in-water emulsion
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.918629/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2022.918629/full

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