Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction

Purpose. In this study, our purpose was to investigate the diagnostic efficacy of the dynamic contrast-enhanced magnetic resonance imaging (MRI) method in the patients with bile duct obstruction. Materials and Methods. 108 consecutive patients (53 men, 55 women, mean age; 55.77±14.62, range...

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Main Authors: Mehmet Bilgin, Hüseyin Toprak, Mehmet Burgazli, S. Sennur Bilgin, Ritvan Chasan, Ali Erdogan, Cem Balci
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/731089
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author Mehmet Bilgin
Hüseyin Toprak
Mehmet Burgazli
S. Sennur Bilgin
Ritvan Chasan
Ali Erdogan
Cem Balci
author_facet Mehmet Bilgin
Hüseyin Toprak
Mehmet Burgazli
S. Sennur Bilgin
Ritvan Chasan
Ali Erdogan
Cem Balci
author_sort Mehmet Bilgin
collection DOAJ
description Purpose. In this study, our purpose was to investigate the diagnostic efficacy of the dynamic contrast-enhanced magnetic resonance imaging (MRI) method in the patients with bile duct obstruction. Materials and Methods. 108 consecutive patients (53 men, 55 women, mean age; 55.77±14.62, range 18–86 years) were included in this study. All the patients underwent conventional upper abdomen MRI using intravenous contrast material (Gd-DTPA) and MRCP in 1.5 Tesla MRI scanner. MRCP images were evaluated together with the T1 and T2w images, and both biliary ducts and surrounding tissues were examined for possible pathologies that may cause obstruction. Results. MRI/MRCP findings compared with final diagnoses, MRI/MRCP in the demonstration of bile duct obstruction sensitivity 96%, the specificity 100%, and accuracy 96.3%, in the detection of presence and level of obstruction, the sensitivity 96.7%, specificity 100%, and accuracy 97.2%, in the diagnosis of choledocholithiasis, the sensitivity 82.3%, specificity 96%, and accuracy 91.7%, and in the determination of the character of the stenosis, sensitivity 95.6%, specificity 91.3%, and accuracy 94.5% were found. Conclusion. The combination of dynamic contrast-enhanced MRI and MRCP techniques in patients with suspected biliary obstruction gives the detailed information about the presence of obstruction, location, and causes and is a highly specific and sensitive method.
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spelling doaj-art-f12c69d58d9e442e8681db1dfea05ca72025-02-03T01:31:14ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/731089731089Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary ObstructionMehmet Bilgin0Hüseyin Toprak1Mehmet Burgazli2S. Sennur Bilgin3Ritvan Chasan4Ali Erdogan5Cem Balci6Department of Radiology, Medical Faculty, Bezmialem Vakif University, 34093 Istanbul, TurkeyDepartment of Radiology, Medical Faculty, Bezmialem Vakif University, 34093 Istanbul, TurkeyDepartment of Internal Medicine, Justus-Liebig-University Hospital, 35392 Giessen, GermanyDepartment of Radiology, Justus-Liebig-University Hospital, 35392 Giessen, GermanyDepartment of Internal Medicine, Justus-Liebig-University Hospital, 35392 Giessen, GermanyDepartment of Internal Medicine, Justus-Liebig-University Hospital, 35392 Giessen, GermanyDepartment of Radiology, Istanbul Bilim University School of Medicine, 34340 Istanbul, TurkeyPurpose. In this study, our purpose was to investigate the diagnostic efficacy of the dynamic contrast-enhanced magnetic resonance imaging (MRI) method in the patients with bile duct obstruction. Materials and Methods. 108 consecutive patients (53 men, 55 women, mean age; 55.77±14.62, range 18–86 years) were included in this study. All the patients underwent conventional upper abdomen MRI using intravenous contrast material (Gd-DTPA) and MRCP in 1.5 Tesla MRI scanner. MRCP images were evaluated together with the T1 and T2w images, and both biliary ducts and surrounding tissues were examined for possible pathologies that may cause obstruction. Results. MRI/MRCP findings compared with final diagnoses, MRI/MRCP in the demonstration of bile duct obstruction sensitivity 96%, the specificity 100%, and accuracy 96.3%, in the detection of presence and level of obstruction, the sensitivity 96.7%, specificity 100%, and accuracy 97.2%, in the diagnosis of choledocholithiasis, the sensitivity 82.3%, specificity 96%, and accuracy 91.7%, and in the determination of the character of the stenosis, sensitivity 95.6%, specificity 91.3%, and accuracy 94.5% were found. Conclusion. The combination of dynamic contrast-enhanced MRI and MRCP techniques in patients with suspected biliary obstruction gives the detailed information about the presence of obstruction, location, and causes and is a highly specific and sensitive method.http://dx.doi.org/10.1100/2012/731089
spellingShingle Mehmet Bilgin
Hüseyin Toprak
Mehmet Burgazli
S. Sennur Bilgin
Ritvan Chasan
Ali Erdogan
Cem Balci
Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction
The Scientific World Journal
title Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction
title_full Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction
title_fullStr Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction
title_full_unstemmed Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction
title_short Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction
title_sort diagnostic value of dynamic contrast enhanced magnetic resonance imaging in the evaluation of the biliary obstruction
url http://dx.doi.org/10.1100/2012/731089
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