The prognostic implications of podoplanin in cancer‐associated fibroblasts and PD‐L1 expression in high‐grade neuroendocrine carcinoma of the lung

The prognostic implications of podoplanin in cancer‐associated fibroblasts and PD‐L1 expression in high‐grade neuroendocrine carcinoma of the lung

Abstract Objectives Podoplanin (PDPN) expression in cancer‐associated fibroblasts (CAFs) (CAF‐PDPN) is considered a poor prognostic factor in nonsmall cell lung cancer, but little is known about its clinical significance in high‐grade neuroendocrine carcinoma of the lung (HGNEC). This study examines...

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Main Authors: Tatsuya Miyamoto, Tomohiro Haruki, Karen Makishima, Shinji Matsui, Yuki Oshima, Yoshihisa Umekita, Hiroshige Nakamura
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Thoracic Cancer
Subjects:
cancer‐associated fibroblast
podoplanin
programmed death‐ligand 1
Online Access:https://doi.org/10.1111/1759-7714.15477
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