Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential
The processing of tropical fruits generates large amounts of residues, such as peels or seeds, with great nutraceutical potential due to their high content of bioactive compounds: polyphenols, carotenoids, anthocyanins, flavonoids, tannins, and phenolic acids with antioxidant, anti-inflammatory, ant...
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Elsevier
2025-06-01
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| Series: | Journal of Agriculture and Food Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666154325003540 |
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| author | Niza Otero-Guzman Ricardo Andrade-Pizarro |
| author_facet | Niza Otero-Guzman Ricardo Andrade-Pizarro |
| author_sort | Niza Otero-Guzman |
| collection | DOAJ |
| description | The processing of tropical fruits generates large amounts of residues, such as peels or seeds, with great nutraceutical potential due to their high content of bioactive compounds: polyphenols, carotenoids, anthocyanins, flavonoids, tannins, and phenolic acids with antioxidant, anti-inflammatory, antimicrobial, anticancer and anti-obesity properties. However, there are several challenges associted with the efficient extraction and accurate characterization of these compounds, including the complexity of plant matrices, variability in compound polarity, and the need for scalable, eco-friendly methods that preserve their bioactivity. This review highlights the bioactive composition, the most important and studied therapeutic properties of the by-products of different tropical fruits such as mango, pineapple, and avocado, and the main extraction, identification, and characterization techniques of these compounds. A scientific surveillance analysis of studies published on the last 5 years revealed a 67.6 % increase in research activity, with a growing emphasis on green extraction technologies—such as ultrasound-assisted, microwave-assisted, and supercritical fluid extraction— and the use of emerging solvents like natural deep eutectic solvents. Moreover, there is increasing interest in optimizing extraction conditions and in validating the functional potential of bioactive compounds through in vitro digestion and bioavailability assays. These trends underscore the strategic relevance of tropical fruit by-products as a sustainable source of functional compounds. The integration of clean technologies, optimization and scale-up strategies, and advanced analytical methods supports their valorization and promotes the development of high value-added nutraceuticals aligned with circular economy principles and public health objectives. |
| format | Article |
| id | doaj-art-f0f9d8c57b9b4c699c19de363f72aa30 |
| institution | OA Journals |
| issn | 2666-1543 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Agriculture and Food Research |
| spelling | doaj-art-f0f9d8c57b9b4c699c19de363f72aa302025-08-20T02:30:55ZengElsevierJournal of Agriculture and Food Research2666-15432025-06-012110198310.1016/j.jafr.2025.101983Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potentialNiza Otero-Guzman0Ricardo Andrade-Pizarro1Corresponding author.; Ph.D. Program in Food Science and Technology, Universidad de Córdoba, Cra. 6 #77-305, Montería, Córdoba, ColombiaPh.D. Program in Food Science and Technology, Universidad de Córdoba, Cra. 6 #77-305, Montería, Córdoba, ColombiaThe processing of tropical fruits generates large amounts of residues, such as peels or seeds, with great nutraceutical potential due to their high content of bioactive compounds: polyphenols, carotenoids, anthocyanins, flavonoids, tannins, and phenolic acids with antioxidant, anti-inflammatory, antimicrobial, anticancer and anti-obesity properties. However, there are several challenges associted with the efficient extraction and accurate characterization of these compounds, including the complexity of plant matrices, variability in compound polarity, and the need for scalable, eco-friendly methods that preserve their bioactivity. This review highlights the bioactive composition, the most important and studied therapeutic properties of the by-products of different tropical fruits such as mango, pineapple, and avocado, and the main extraction, identification, and characterization techniques of these compounds. A scientific surveillance analysis of studies published on the last 5 years revealed a 67.6 % increase in research activity, with a growing emphasis on green extraction technologies—such as ultrasound-assisted, microwave-assisted, and supercritical fluid extraction— and the use of emerging solvents like natural deep eutectic solvents. Moreover, there is increasing interest in optimizing extraction conditions and in validating the functional potential of bioactive compounds through in vitro digestion and bioavailability assays. These trends underscore the strategic relevance of tropical fruit by-products as a sustainable source of functional compounds. The integration of clean technologies, optimization and scale-up strategies, and advanced analytical methods supports their valorization and promotes the development of high value-added nutraceuticals aligned with circular economy principles and public health objectives.http://www.sciencedirect.com/science/article/pii/S2666154325003540AntioxidantsHealth benefitsPhytochemicalsGreen technologiesBioaccessibility |
| spellingShingle | Niza Otero-Guzman Ricardo Andrade-Pizarro Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential Journal of Agriculture and Food Research Antioxidants Health benefits Phytochemicals Green technologies Bioaccessibility |
| title | Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential |
| title_full | Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential |
| title_fullStr | Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential |
| title_full_unstemmed | Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential |
| title_short | Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential |
| title_sort | bioactive compounds from tropical fruit by products extraction characterization and therapeutic potential |
| topic | Antioxidants Health benefits Phytochemicals Green technologies Bioaccessibility |
| url | http://www.sciencedirect.com/science/article/pii/S2666154325003540 |
| work_keys_str_mv | AT nizaoteroguzman bioactivecompoundsfromtropicalfruitbyproductsextractioncharacterizationandtherapeuticpotential AT ricardoandradepizarro bioactivecompoundsfromtropicalfruitbyproductsextractioncharacterizationandtherapeuticpotential |