Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of Buryatia
Evidential base for diagnosis and treatment of myocardial infarction is based on the results of randomized clinical studies that included mostly male patients. Objective: to determine gender specifics in development, progression, methods of treatment, diagnostics, outcomes of myocardial infarction f...
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2017-09-01
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| Series: | Acta Biomedica Scientifica |
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| Online Access: | https://www.actabiomedica.ru/jour/article/view/506 |
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| author | L. B. Sodnomova N. O. Bulutova |
| author_facet | L. B. Sodnomova N. O. Bulutova |
| author_sort | L. B. Sodnomova |
| collection | DOAJ |
| description | Evidential base for diagnosis and treatment of myocardial infarction is based on the results of randomized clinical studies that included mostly male patients. Objective: to determine gender specifics in development, progression, methods of treatment, diagnostics, outcomes of myocardial infarction for defining customized approaches to its treatment. Study material and methods: 84 medical records of patients with myocardial infarction - 50 male and 54 female patients admitted in the emergency cardiac care department. Statistical data is processed in Microsoft Excel and Statistica v. 10.0. Results. Female patients suffer myocardial infarction late in life; they display higher obesity rate, renal dysfunction, type 2 diabetes as compared to male patients. At the time of admission to hospital the risk of hemorrhage is higher among female patients, which is related to the higher rate of renal disfunction and age. Average CRUSADE score for female patients is 39.14 ± 2.5, for male patients - 22.7 ± 1.4 points. Female patients demonstrate higher frequency of atypical symptoms for myocardial infarction - 18 %, compared to 8 % for males (р = 0.05), that leads to prolongated period of symptom-hospitalization. Thus, there are less women who are hospitalized within first 3 hours - 6 % against 28 % men (р = 0.01). Women display tendency to a higher frequency of Q-negative and recurrent myocardial infarctions, men - to first-time and Q-positive infarctions. As for the frequency of CAG, TLT and PCI, as well as mortality rate due to MI there is no difference between the groups. |
| format | Article |
| id | doaj-art-f0d45bcd7b3b435fafd3fb5ff7dd04b9 |
| institution | Kabale University |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| publishDate | 2017-09-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj-art-f0d45bcd7b3b435fafd3fb5ff7dd04b92025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962017-09-0125(2)495410.12737/article_5a3a0dbc1a5221.80743076506Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of BuryatiaL. B. Sodnomova0N. O. Bulutova1N.A. Semashko Republican Clinical HospitalN.A. Semashko Republican Clinical HospitalEvidential base for diagnosis and treatment of myocardial infarction is based on the results of randomized clinical studies that included mostly male patients. Objective: to determine gender specifics in development, progression, methods of treatment, diagnostics, outcomes of myocardial infarction for defining customized approaches to its treatment. Study material and methods: 84 medical records of patients with myocardial infarction - 50 male and 54 female patients admitted in the emergency cardiac care department. Statistical data is processed in Microsoft Excel and Statistica v. 10.0. Results. Female patients suffer myocardial infarction late in life; they display higher obesity rate, renal dysfunction, type 2 diabetes as compared to male patients. At the time of admission to hospital the risk of hemorrhage is higher among female patients, which is related to the higher rate of renal disfunction and age. Average CRUSADE score for female patients is 39.14 ± 2.5, for male patients - 22.7 ± 1.4 points. Female patients demonstrate higher frequency of atypical symptoms for myocardial infarction - 18 %, compared to 8 % for males (р = 0.05), that leads to prolongated period of symptom-hospitalization. Thus, there are less women who are hospitalized within first 3 hours - 6 % against 28 % men (р = 0.01). Women display tendency to a higher frequency of Q-negative and recurrent myocardial infarctions, men - to first-time and Q-positive infarctions. As for the frequency of CAG, TLT and PCI, as well as mortality rate due to MI there is no difference between the groups.https://www.actabiomedica.ru/jour/article/view/506myocardial infarction (im)gender specificsmortalityrevascularization |
| spellingShingle | L. B. Sodnomova N. O. Bulutova Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of Buryatia Acta Biomedica Scientifica myocardial infarction (im) gender specifics mortality revascularization |
| title | Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of Buryatia |
| title_full | Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of Buryatia |
| title_fullStr | Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of Buryatia |
| title_full_unstemmed | Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of Buryatia |
| title_short | Gender differences for myocardial infarction in ACS outcome with ST elevation in the Republic of Buryatia |
| title_sort | gender differences for myocardial infarction in acs outcome with st elevation in the republic of buryatia |
| topic | myocardial infarction (im) gender specifics mortality revascularization |
| url | https://www.actabiomedica.ru/jour/article/view/506 |
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