Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management
The emergence and spread of the highly contagious novel coronavirus disease (COVID-19) have triggered the greatest public health challenge of the last century. Aside from being a primary respiratory disease, acute ischemic stroke has emerged as a complication of the disease. While current evidence s...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2020/7397480 |
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| _version_ | 1832550876470837248 |
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| author | Ademola S. Ojo Simon A. Balogun Ahmed O. Idowu |
| author_facet | Ademola S. Ojo Simon A. Balogun Ahmed O. Idowu |
| author_sort | Ademola S. Ojo |
| collection | DOAJ |
| description | The emergence and spread of the highly contagious novel coronavirus disease (COVID-19) have triggered the greatest public health challenge of the last century. Aside from being a primary respiratory disease, acute ischemic stroke has emerged as a complication of the disease. While current evidence shows COVID-19 could cause ischemic stroke especially in severe disease, there are similarities in the risk factors for severe COVID-19 as well as ischemic stroke, underscoring the complex relationship between these two conditions. The pandemic has created challenges for acute stroke care. Rapid assessment and time-sensitive interventions required for optimum outcomes in acute stroke care have been complicated by COVID-19 due to the need for disease transmission preventive measures. The purpose of this article is to explore the putative mechanisms of ischemic stroke in COVID-19 and the clinical characteristics of COVID-19 patients who develop ischemic stroke. In addition, we discuss the challenges of managing acute ischemic stroke in the setting of COVID-19 and review current management guidelines. We also highlighted potential areas for future research. |
| format | Article |
| id | doaj-art-f0b5037fda79444aa2ac9bbc05e7c0c9 |
| institution | Kabale University |
| issn | 2090-1852 2090-1860 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neurology Research International |
| spelling | doaj-art-f0b5037fda79444aa2ac9bbc05e7c0c92025-02-03T06:05:44ZengWileyNeurology Research International2090-18522090-18602020-01-01202010.1155/2020/73974807397480Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and ManagementAdemola S. Ojo0Simon A. Balogun1Ahmed O. Idowu2Department of Anatomical Sciences, St. George’s University School of Medicine, St. George’s, GrenadaDepartment of Neurological Surgery, Obafemi Awolowo University Teaching Hospital Complex, Ile Ife, NigeriaNeurology Division, Department of Medicine, Obafemi Awolowo University Teaching Hospital Complex, Ile Ife, NigeriaThe emergence and spread of the highly contagious novel coronavirus disease (COVID-19) have triggered the greatest public health challenge of the last century. Aside from being a primary respiratory disease, acute ischemic stroke has emerged as a complication of the disease. While current evidence shows COVID-19 could cause ischemic stroke especially in severe disease, there are similarities in the risk factors for severe COVID-19 as well as ischemic stroke, underscoring the complex relationship between these two conditions. The pandemic has created challenges for acute stroke care. Rapid assessment and time-sensitive interventions required for optimum outcomes in acute stroke care have been complicated by COVID-19 due to the need for disease transmission preventive measures. The purpose of this article is to explore the putative mechanisms of ischemic stroke in COVID-19 and the clinical characteristics of COVID-19 patients who develop ischemic stroke. In addition, we discuss the challenges of managing acute ischemic stroke in the setting of COVID-19 and review current management guidelines. We also highlighted potential areas for future research.http://dx.doi.org/10.1155/2020/7397480 |
| spellingShingle | Ademola S. Ojo Simon A. Balogun Ahmed O. Idowu Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management Neurology Research International |
| title | Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management |
| title_full | Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management |
| title_fullStr | Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management |
| title_full_unstemmed | Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management |
| title_short | Acute Ischemic Stroke in COVID-19: Putative Mechanisms, Clinical Characteristics, and Management |
| title_sort | acute ischemic stroke in covid 19 putative mechanisms clinical characteristics and management |
| url | http://dx.doi.org/10.1155/2020/7397480 |
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