Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers
BACKGROUND: Although centrilobular emphysema, and small airway, interstitial and alveoli inflammation can be detected pathologically in the lungs of smokers with relatively well preserved lung function, these changes are difficult to assess using available physiological tests. Because submaximal sin...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
1998-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/1998/324920 |
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| _version_ | 1832555963840724992 |
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| author | DJ Cotton JT Mink BL Graham |
| author_facet | DJ Cotton JT Mink BL Graham |
| author_sort | DJ Cotton |
| collection | DOAJ |
| description | BACKGROUND: Although centrilobular emphysema, and small airway, interstitial and alveoli inflammation can be detected pathologically in the lungs of smokers with relatively well preserved lung function, these changes are difficult to assess using available physiological tests. Because submaximal single breath washout (SBWSM) manoeuvres improve the detection of abnormalities in ventilation inhomogeneity in the lung periphery in smokers compared with traditional vital capacity manoeuvres, SBWSM manoeuvres were used in this study to measure temporal differences in diffusing capacity using a rapid response carbon monoxide analyzer. |
| format | Article |
| id | doaj-art-f0b02d7774014107a75658d049353748 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 1998-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-f0b02d7774014107a75658d0493537482025-02-03T05:46:49ZengWileyCanadian Respiratory Journal1198-22411998-01-015210110810.1155/1998/324920Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in SmokersDJ Cotton0JT Mink1BL Graham2Division of Respiratory Medicine, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaDivision of Respiratory Medicine, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaDivision of Respiratory Medicine, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, CanadaBACKGROUND: Although centrilobular emphysema, and small airway, interstitial and alveoli inflammation can be detected pathologically in the lungs of smokers with relatively well preserved lung function, these changes are difficult to assess using available physiological tests. Because submaximal single breath washout (SBWSM) manoeuvres improve the detection of abnormalities in ventilation inhomogeneity in the lung periphery in smokers compared with traditional vital capacity manoeuvres, SBWSM manoeuvres were used in this study to measure temporal differences in diffusing capacity using a rapid response carbon monoxide analyzer.http://dx.doi.org/10.1155/1998/324920 |
| spellingShingle | DJ Cotton JT Mink BL Graham Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers Canadian Respiratory Journal |
| title | Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers |
| title_full | Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers |
| title_fullStr | Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers |
| title_full_unstemmed | Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers |
| title_short | Nonuniformity of Diffusing Capacity From Small Alveolar Gas Samples Is Increased in Smokers |
| title_sort | nonuniformity of diffusing capacity from small alveolar gas samples is increased in smokers |
| url | http://dx.doi.org/10.1155/1998/324920 |
| work_keys_str_mv | AT djcotton nonuniformityofdiffusingcapacityfromsmallalveolargassamplesisincreasedinsmokers AT jtmink nonuniformityofdiffusingcapacityfromsmallalveolargassamplesisincreasedinsmokers AT blgraham nonuniformityofdiffusingcapacityfromsmallalveolargassamplesisincreasedinsmokers |