A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASE

A history case of severe juvenile arthritis with uveitis as manifestations of Crohn’s disease, resistant to standard immunosuppressive therapy and treatment with chimeric anti-tumor necrosis factor-alpha monoclonal antibody is represented in this article. Adalimumab — recombinant monoclonal antibody...

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Main Authors: V. A. Malievskii, A. A. Nijevitch, E. P. Pervushina, L. Yu. Sapronova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2013-07-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/323
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author V. A. Malievskii
A. A. Nijevitch
E. P. Pervushina
L. Yu. Sapronova
author_facet V. A. Malievskii
A. A. Nijevitch
E. P. Pervushina
L. Yu. Sapronova
author_sort V. A. Malievskii
collection DOAJ
description A history case of severe juvenile arthritis with uveitis as manifestations of Crohn’s disease, resistant to standard immunosuppressive therapy and treatment with chimeric anti-tumor necrosis factor-alpha monoclonal antibody is represented in this article. Adalimumab — recombinant monoclonal antibody, which peptides sequence is identical to human IgG1, allowed to arrest active stage of inflammatory process, uveitis and intestinal manifestations of Crohn’s disease, as well as to restore function of involved joints almost completely. This history case confirms high efficacy of adalimumab in patients with Crohn’s disease manifested with juvenile arthritis complicated with uveitis, and allow to recommend this medicine as first-line genetically-engineered biological agent in treatment of such patients.
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institution Kabale University
issn 1682-5527
1682-5535
language English
publishDate 2013-07-01
publisher "Paediatrician" Publishers LLC
record_format Article
series Вопросы современной педиатрии
spelling doaj-art-f099b360d7994a91bab2902fbfdff02c2025-08-20T03:57:26Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352013-07-0112418118410.15690/vsp.v12i4.749323A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASEV. A. Malievskii0A. A. Nijevitch1E. P. Pervushina2L. Yu. Sapronova3Bashkortostan State Medical University, Ufa, Republic of BashkortostanBashkortostan State Medical University, Ufa, Republic of BashkortostanRepublican Pediatric Clinical Hospital, UfaRepublican Pediatric Clinical Hospital, UfaA history case of severe juvenile arthritis with uveitis as manifestations of Crohn’s disease, resistant to standard immunosuppressive therapy and treatment with chimeric anti-tumor necrosis factor-alpha monoclonal antibody is represented in this article. Adalimumab — recombinant monoclonal antibody, which peptides sequence is identical to human IgG1, allowed to arrest active stage of inflammatory process, uveitis and intestinal manifestations of Crohn’s disease, as well as to restore function of involved joints almost completely. This history case confirms high efficacy of adalimumab in patients with Crohn’s disease manifested with juvenile arthritis complicated with uveitis, and allow to recommend this medicine as first-line genetically-engineered biological agent in treatment of such patients.https://vsp.spr-journal.ru/jour/article/view/323childrenjuvenile arthritisuveitiscrohn’s diseaseadalimumab
spellingShingle V. A. Malievskii
A. A. Nijevitch
E. P. Pervushina
L. Yu. Sapronova
A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASE
Вопросы современной педиатрии
children
juvenile arthritis
uveitis
crohn’s disease
adalimumab
title A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASE
title_full A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASE
title_fullStr A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASE
title_full_unstemmed A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASE
title_short A HISTORY CASE OF ADALIMUMAB TREATMENT IN A FEMALE PATIENT WITH JUVENILE ARTHRITIS AND UVEITIS AS MANIFESTATIONS OF CROHN’S DISEASE
title_sort history case of adalimumab treatment in a female patient with juvenile arthritis and uveitis as manifestations of crohn s disease
topic children
juvenile arthritis
uveitis
crohn’s disease
adalimumab
url https://vsp.spr-journal.ru/jour/article/view/323
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