Extensive T-Cell Profiling Following SARS-CoV-2 mRNA Vaccination in Multiple Sclerosis Patients Treated with DMTs

Extensive T-Cell Profiling Following SARS-CoV-2 mRNA Vaccination in Multiple Sclerosis Patients Treated with DMTs

Disease-modifying therapies (DMTs) are known to impact cellular and humoral immune response in persons with multiple sclerosis (pwMS). In this study, we performed in-depth SARS-CoV-2-specific T-cell profiling using flow cytometry. T-cell immunity in pwMS with or without DMTs was evaluated before a f...

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Bibliographic Details
Main Authors: Hannah Solchenberger, Marcus Odendahl, Dirk Schriefer, Undine Proschmann, Georges Katoul al Rahbani, Tjalf Ziemssen, Katja Akgün
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pathogens
Subjects:
multiple sclerosis
mRNA vaccines
SARS-CoV-2
disease-modifying therapy
anti-CD20 treatment
sphingosine-1-phosphate receptor modulation
Online Access:https://www.mdpi.com/2076-0817/14/3/235
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