The association between body roundness index and mortality in diabetes
Abstract Background The association between body roundness index (BRI) and all-cause mortality and the occurrence of cardiovascular disease (CVD) in patients with diabetes is unknown. This study aimed to determine the association between BRI and all-cause/CVD mortality in a diabetic cohort. Methods...
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BMC
2025-04-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-025-04689-6 |
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| author | Han Liu Haowen Ye Xiaofang Zhang Yun Wen Jiaxin Wang Meixin Yu Xian Yang Caixia Ma Liangyan Wu Yongting Zhao Lihong Wang |
| author_facet | Han Liu Haowen Ye Xiaofang Zhang Yun Wen Jiaxin Wang Meixin Yu Xian Yang Caixia Ma Liangyan Wu Yongting Zhao Lihong Wang |
| author_sort | Han Liu |
| collection | DOAJ |
| description | Abstract Background The association between body roundness index (BRI) and all-cause mortality and the occurrence of cardiovascular disease (CVD) in patients with diabetes is unknown. This study aimed to determine the association between BRI and all-cause/CVD mortality in a diabetic cohort. Methods A total of 8227 individuals with diabetes from the 1999–2018 National Health and Nutrition Examination Survey (NHANES) database were included. Multifactorial Cox regression models were used to analyze the association between BRI and mortality in patients with diabetes. Multivariate-adjusted restricted cubic spline (RCS) regression was used to test for nonlinearity. Results During a median follow-up of 7.25 years, a total of 27.22% died, with 9.18% of these deaths due to CVD. After fully adjusting for potential confounders, BRI remained significantly associated with all-cause/CVD mortality in the diabetic population. The restricted cubic splines revealed no significant nonlinear relationship between BRI and all-cause mortality (P = 0.29) or CVD mortality (P = 0.73). BRI was better associated with all-cause/CVD mortality in patients with diabetes compared to other body metabolic indices. Conclusions In patients with diabetes, we found an association between BRI and all-cause/CVD mortality. |
| format | Article |
| id | doaj-art-f094bdfbf64446bf88f3adad3eb6f52c |
| institution | DOAJ |
| issn | 1471-2261 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-f094bdfbf64446bf88f3adad3eb6f52c2025-08-20T03:06:48ZengBMCBMC Cardiovascular Disorders1471-22612025-04-0125111110.1186/s12872-025-04689-6The association between body roundness index and mortality in diabetesHan Liu0Haowen Ye1Xiaofang Zhang2Yun Wen3Jiaxin Wang4Meixin Yu5Xian Yang6Caixia Ma7Liangyan Wu8Yongting Zhao9Lihong Wang10Department of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityThe Academician Cooperative Laboratory of Basic and Translational Research on Chronic DiseasesDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Jinan UniversityAbstract Background The association between body roundness index (BRI) and all-cause mortality and the occurrence of cardiovascular disease (CVD) in patients with diabetes is unknown. This study aimed to determine the association between BRI and all-cause/CVD mortality in a diabetic cohort. Methods A total of 8227 individuals with diabetes from the 1999–2018 National Health and Nutrition Examination Survey (NHANES) database were included. Multifactorial Cox regression models were used to analyze the association between BRI and mortality in patients with diabetes. Multivariate-adjusted restricted cubic spline (RCS) regression was used to test for nonlinearity. Results During a median follow-up of 7.25 years, a total of 27.22% died, with 9.18% of these deaths due to CVD. After fully adjusting for potential confounders, BRI remained significantly associated with all-cause/CVD mortality in the diabetic population. The restricted cubic splines revealed no significant nonlinear relationship between BRI and all-cause mortality (P = 0.29) or CVD mortality (P = 0.73). BRI was better associated with all-cause/CVD mortality in patients with diabetes compared to other body metabolic indices. Conclusions In patients with diabetes, we found an association between BRI and all-cause/CVD mortality.https://doi.org/10.1186/s12872-025-04689-6Body roundness indexDiabetesAll-cause mortalityCardiovascular disease |
| spellingShingle | Han Liu Haowen Ye Xiaofang Zhang Yun Wen Jiaxin Wang Meixin Yu Xian Yang Caixia Ma Liangyan Wu Yongting Zhao Lihong Wang The association between body roundness index and mortality in diabetes BMC Cardiovascular Disorders Body roundness index Diabetes All-cause mortality Cardiovascular disease |
| title | The association between body roundness index and mortality in diabetes |
| title_full | The association between body roundness index and mortality in diabetes |
| title_fullStr | The association between body roundness index and mortality in diabetes |
| title_full_unstemmed | The association between body roundness index and mortality in diabetes |
| title_short | The association between body roundness index and mortality in diabetes |
| title_sort | association between body roundness index and mortality in diabetes |
| topic | Body roundness index Diabetes All-cause mortality Cardiovascular disease |
| url | https://doi.org/10.1186/s12872-025-04689-6 |
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