A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs

A functional analysis of 180 cancer cell lines reveals conserved intrinsic metabolic programs

Abstract Cancer cells reprogram their metabolism to support growth and invasion. While previous work has highlighted how single altered reactions and pathways can drive tumorigenesis, it remains unclear how individual changes propagate at the network level and eventually determine global metabolic a...

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Bibliographic Details
Main Authors: Sarah Cherkaoui, Stephan Durot, Jenna Bradley, Susan Critchlow, Sebastien Dubuis, Mauro Miguel Masiero, Rebekka Wegmann, Berend Snijder, Alaa Othman, Claus Bendtsen, Nicola Zamboni
Format: Article
Language:English
Published: Springer Nature 2022-11-01
Series:Molecular Systems Biology
Subjects:
cancer metabolism
cell lines
metabolomics
metabolic flux
omics
Online Access:https://doi.org/10.15252/msb.202211033
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https://doi.org/10.15252/msb.202211033

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