Long-term drought and risk of infant mortality in Africa: A cross-sectional study.
<h4>Background</h4>As extreme events such as drought and flood are projected to increase in frequency and intensity under climate change, there is still large missing evidence on how drought exposure potentially impacts mortality among young children. This study aimed to investigate the...
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS Medicine |
| Online Access: | https://doi.org/10.1371/journal.pmed.1004516 |
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| author | Pin Wang Tormod Rogne Joshua L Warren Ernest O Asare Robert A Akum N'datchoh E Toure Joseph S Ross Kai Chen |
| author_facet | Pin Wang Tormod Rogne Joshua L Warren Ernest O Asare Robert A Akum N'datchoh E Toure Joseph S Ross Kai Chen |
| author_sort | Pin Wang |
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| description | <h4>Background</h4>As extreme events such as drought and flood are projected to increase in frequency and intensity under climate change, there is still large missing evidence on how drought exposure potentially impacts mortality among young children. This study aimed to investigate the association between drought and risk of infant mortality in Africa, a region highly vulnerable to climate change that bears the heaviest share of the global burden.<h4>Methods and findings</h4>In this cross-sectional study, we obtained data on infant mortality in 34 African countries during 1992-2019 from the Demographic and Health Surveys program. We measured drought by the standardized precipitation evapotranspiration index at a timescale of 24 months and a spatial resolution of 10 × 10 km, which was further dichotomized into mild and severe drought. The association between drought exposure and infant mortality risk was estimated using Cox regression models allowing time-dependent covariates. We further examined whether the association varied for neonatal and post-neonatal mortality and whether there was a delayed association with drought exposure during pregnancy or infancy. The mean (standard deviation) number of months in which children experienced any drought during pregnancy and survival period (from birth through death before 1 year of age) was 4.6 (5.2) and 7.3 (7.4) among cases and non-cases, respectively. Compared to children who did not experience drought, we did not find evidence that any drought exposure was associated with an increased risk of infant mortality (hazard ratio [HR]: 1.02, 95% confidence interval [CI] [1.00, 1.04], p = 0.072). When stratified by drought severity, we found a statistically significant association with severe drought (HR: 1.04; 95% CI [1.01, 1.07], p = 0.015), but no significant association with mild drought (HR: 1.01; 95% CI [0.99, 1.03], p = 0.353), compared to non-exposure to any drought. However, when excluding drought exposure during pregnancy, the association with severe drought was found to be non-significant. In addition, an increased risk of neonatal mortality was associated with severe drought (HR: 1.05; 95% CI [1.01, 1.10], p = 0.019), but not with mild drought (HR: 0.99; 95% CI [0.96, 1.02], p = 0.657).<h4>Conclusions</h4>Exposure to long-term severe drought was associated with increased infant mortality risk in Africa. Our findings urge more effective adaptation measures and alleviation strategies against the adverse impact of drought on child health. |
| format | Article |
| id | doaj-art-f07d915cfa074f598900a9d5d2e25ed7 |
| institution | Kabale University |
| issn | 1549-1277 1549-1676 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
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| spelling | doaj-art-f07d915cfa074f598900a9d5d2e25ed72025-02-07T05:30:21ZengPublic Library of Science (PLoS)PLoS Medicine1549-12771549-16762025-01-01221e100451610.1371/journal.pmed.1004516Long-term drought and risk of infant mortality in Africa: A cross-sectional study.Pin WangTormod RogneJoshua L WarrenErnest O AsareRobert A AkumN'datchoh E ToureJoseph S RossKai Chen<h4>Background</h4>As extreme events such as drought and flood are projected to increase in frequency and intensity under climate change, there is still large missing evidence on how drought exposure potentially impacts mortality among young children. This study aimed to investigate the association between drought and risk of infant mortality in Africa, a region highly vulnerable to climate change that bears the heaviest share of the global burden.<h4>Methods and findings</h4>In this cross-sectional study, we obtained data on infant mortality in 34 African countries during 1992-2019 from the Demographic and Health Surveys program. We measured drought by the standardized precipitation evapotranspiration index at a timescale of 24 months and a spatial resolution of 10 × 10 km, which was further dichotomized into mild and severe drought. The association between drought exposure and infant mortality risk was estimated using Cox regression models allowing time-dependent covariates. We further examined whether the association varied for neonatal and post-neonatal mortality and whether there was a delayed association with drought exposure during pregnancy or infancy. The mean (standard deviation) number of months in which children experienced any drought during pregnancy and survival period (from birth through death before 1 year of age) was 4.6 (5.2) and 7.3 (7.4) among cases and non-cases, respectively. Compared to children who did not experience drought, we did not find evidence that any drought exposure was associated with an increased risk of infant mortality (hazard ratio [HR]: 1.02, 95% confidence interval [CI] [1.00, 1.04], p = 0.072). When stratified by drought severity, we found a statistically significant association with severe drought (HR: 1.04; 95% CI [1.01, 1.07], p = 0.015), but no significant association with mild drought (HR: 1.01; 95% CI [0.99, 1.03], p = 0.353), compared to non-exposure to any drought. However, when excluding drought exposure during pregnancy, the association with severe drought was found to be non-significant. In addition, an increased risk of neonatal mortality was associated with severe drought (HR: 1.05; 95% CI [1.01, 1.10], p = 0.019), but not with mild drought (HR: 0.99; 95% CI [0.96, 1.02], p = 0.657).<h4>Conclusions</h4>Exposure to long-term severe drought was associated with increased infant mortality risk in Africa. Our findings urge more effective adaptation measures and alleviation strategies against the adverse impact of drought on child health.https://doi.org/10.1371/journal.pmed.1004516 |
| spellingShingle | Pin Wang Tormod Rogne Joshua L Warren Ernest O Asare Robert A Akum N'datchoh E Toure Joseph S Ross Kai Chen Long-term drought and risk of infant mortality in Africa: A cross-sectional study. PLoS Medicine |
| title | Long-term drought and risk of infant mortality in Africa: A cross-sectional study. |
| title_full | Long-term drought and risk of infant mortality in Africa: A cross-sectional study. |
| title_fullStr | Long-term drought and risk of infant mortality in Africa: A cross-sectional study. |
| title_full_unstemmed | Long-term drought and risk of infant mortality in Africa: A cross-sectional study. |
| title_short | Long-term drought and risk of infant mortality in Africa: A cross-sectional study. |
| title_sort | long term drought and risk of infant mortality in africa a cross sectional study |
| url | https://doi.org/10.1371/journal.pmed.1004516 |
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