Retinoic acid-inducible gene-I aggravates neuroinflammation in early brain injury after subarachnoid hemorrhage through mediating brain microvascular endothelial cell pyroptosis

Retinoic acid-inducible gene-I aggravates neuroinflammation in early brain injury after subarachnoid hemorrhage through mediating brain microvascular endothelial cell pyroptosis

Retinoic acid-inducible gene-I (RIG-I) is an immune signal that promotes inflammatory responses and plays an important role in endothelial cell-mediated inflammation. Currently, no studies have investigated the role of RIG-I in early brain injury (EBI) after subarachnoid hemorrhage (SAH). In this re...

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Bibliographic Details
Main Authors: Bowen Sun, Yuchen Li, Shuai Lan, Xi-ao Wang, Yeping Ling, Harshal Sawant, Bohan Zhang, Jinshuo Yang, Jinju Wang, Pei Wu, Shancai Xu, Ji Bihl, Huaizhang Shi
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Neurotherapeutics
Subjects:
Subarachnoid hemorrhage
Neuroinflammation
Brain microvascular endothelial cells
Pyroptosis
Retinoic acid-inducible gene I
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747925000509
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