Mechanism of DNASE1L3 delaying renal fibrosis by inhibiting PI3K-AKT signaling pathway

Mechanism of DNASE1L3 delaying renal fibrosis by inhibiting PI3K-AKT signaling pathway

Objective To investigate the role and mechanism of deoxyribonuclease 1L3 (DNASE1L3) in renal fibrosis. Methods The renal fibrosis model in vivo was established by unilateral ureteral obstruction in mice. The mRNA and protein expression levels of DNASE1L3 in the kidney were detected by RT-qPCR and WB...

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Bibliographic Details
Main Authors:	WEI Xiao, YU Hong, YUAN Yuan, KUANG Qihui, WANG Xiong, YANG Jun, LUO Pengcheng
Format:	Article
Language:	zho
Published:	Editorial Office of New Medicine 2025-05-01
Series:	Yixue xinzhi zazhi
Subjects:	chronic kidney disease renal fibrosis dnase1l3 pi3k-akt
Online Access:	https://yxxz.whuznhmedj.com/futureApi/storage/attach/2505/ekdPKXzsoJlyIWSdIA4KL6VmCHy5FfRBZsRi6jSc.pdf
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