A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics
Implantable LED light sources have received a lot of attention in the field of optogenetic neuromodulation. This type of light modulation enables effective stimulation of neurons. However, as optogenetics moves towards clinical trials, combinatorial photostimulation based on arrays of LED light sour...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | International Journal of Distributed Sensor Networks |
| Online Access: | http://dx.doi.org/10.1155/2024/5562848 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559319178018816 |
|---|---|
| author | Yanping Ji Chuanzhen Liu Jiawei Li Wensi Wang Mengyi Zheng |
| author_facet | Yanping Ji Chuanzhen Liu Jiawei Li Wensi Wang Mengyi Zheng |
| author_sort | Yanping Ji |
| collection | DOAJ |
| description | Implantable LED light sources have received a lot of attention in the field of optogenetic neuromodulation. This type of light modulation enables effective stimulation of neurons. However, as optogenetics moves towards clinical trials, combinatorial photostimulation based on arrays of LED light sources has emerged. This approach inevitably brings about a large increase in transient temperature, resulting in the inability to achieve precise stimulation of cells. We designed a wireless optogenetic hardware system to realize the control of the stimulation mode and temperature of the light source array. At the same time, a set of combined photothermal physical model was established to simulate the photothermal response of the whole experiment. The physical model can effectively guide the wireless optogenetic hardware circuits to perform effective stimulation within a controlled temperature range. Our model provides a new technical approach for photothermal studies in optogenetic clinical trials. |
| format | Article |
| id | doaj-art-f05d2bcf6a0f454ba036882b30ee5a39 |
| institution | Kabale University |
| issn | 1550-1477 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Distributed Sensor Networks |
| spelling | doaj-art-f05d2bcf6a0f454ba036882b30ee5a392025-02-03T01:30:21ZengWileyInternational Journal of Distributed Sensor Networks1550-14772024-01-01202410.1155/2024/5562848A Photothermal Modelling Approach for Micro-LED Arrays in Wireless OptogeneticsYanping Ji0Chuanzhen Liu1Jiawei Li2Wensi Wang3Mengyi Zheng4Faculty of Information TechnologyFaculty of Information TechnologyFaculty of Information TechnologyFaculty of Information TechnologySchool of SociologyImplantable LED light sources have received a lot of attention in the field of optogenetic neuromodulation. This type of light modulation enables effective stimulation of neurons. However, as optogenetics moves towards clinical trials, combinatorial photostimulation based on arrays of LED light sources has emerged. This approach inevitably brings about a large increase in transient temperature, resulting in the inability to achieve precise stimulation of cells. We designed a wireless optogenetic hardware system to realize the control of the stimulation mode and temperature of the light source array. At the same time, a set of combined photothermal physical model was established to simulate the photothermal response of the whole experiment. The physical model can effectively guide the wireless optogenetic hardware circuits to perform effective stimulation within a controlled temperature range. Our model provides a new technical approach for photothermal studies in optogenetic clinical trials.http://dx.doi.org/10.1155/2024/5562848 |
| spellingShingle | Yanping Ji Chuanzhen Liu Jiawei Li Wensi Wang Mengyi Zheng A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics International Journal of Distributed Sensor Networks |
| title | A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics |
| title_full | A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics |
| title_fullStr | A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics |
| title_full_unstemmed | A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics |
| title_short | A Photothermal Modelling Approach for Micro-LED Arrays in Wireless Optogenetics |
| title_sort | photothermal modelling approach for micro led arrays in wireless optogenetics |
| url | http://dx.doi.org/10.1155/2024/5562848 |
| work_keys_str_mv | AT yanpingji aphotothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT chuanzhenliu aphotothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT jiaweili aphotothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT wensiwang aphotothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT mengyizheng aphotothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT yanpingji photothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT chuanzhenliu photothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT jiaweili photothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT wensiwang photothermalmodellingapproachformicroledarraysinwirelessoptogenetics AT mengyizheng photothermalmodellingapproachformicroledarraysinwirelessoptogenetics |