NEW ORAL ANTICOAGULANTS IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION AND CHRONIC KIDNEY DISEASE
About 10% of the adult population is diagnosed with chronic kidney disease (CKD), and its presence is associated with a high risk of developing cardiovascular diseases including ventricular fibrillation (VF). The long-term monitoring of patients has found a clear association between the degree of re...
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| Main Author: | |
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| Format: | Article |
| Language: | Russian |
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«REMEDIUM GROUP» Ltd.
2015-12-01
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| Series: | Атеротромбоз |
| Subjects: | |
| Online Access: | https://www.aterotromboz.ru/jour/article/view/47 |
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| Summary: | About 10% of the adult population is diagnosed with chronic kidney disease (CKD), and its presence is associated with a high risk of developing cardiovascular diseases including ventricular fibrillation (VF). The long-term monitoring of patients has found a clear association between the degree of renal failure and risk of VF development. ARIC (1) study showed that a relative risk of VF development in patients with glomerular filtration rate (GFR) 15-29 ml/min was 3.2 (95% CI 2.0-5.0), and in patients with normal GFR 1.3 (95% CI 1.1-1.6), p < 0.0001. GFR reduction is an independent predictor of VF development. The mechanism underlying the link between renal failure and risk of VF development is not fully clear. |
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| ISSN: | 2307-1109 2658-5952 |