Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov model
[Objective] To develop a comprehensive health economics evaluation model for HIV blood screening using Markov modeling, so as to evaluate the quality-of-life adjustment years (QALYs) gained by transfusion recipients after implementation of blood HIV screening. [Methods] Shenzhen Blood Center was sel...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Institute of Blood Transfusion of Chinese Academy of Medical Sciences
2025-07-01
|
| Series: | Zhongguo shuxue zazhi |
| Subjects: | |
| Online Access: | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.07.014&lang=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849252836222697472 |
|---|---|
| author | HUANG Liqin WANG Lilin WU Linfen ZUO Jiahui ZENG Jinfeng |
| author_facet | HUANG Liqin WANG Lilin WU Linfen ZUO Jiahui ZENG Jinfeng |
| author_sort | HUANG Liqin |
| collection | DOAJ |
| description | [Objective] To develop a comprehensive health economics evaluation model for HIV blood screening using Markov modeling, so as to evaluate the quality-of-life adjustment years (QALYs) gained by transfusion recipients after implementation of blood HIV screening. [Methods] Shenzhen Blood Center was selected as the validation case for model development. Based on historical HIV screening data of Shenzhen Blood Center and published literature, the health economics evaluation of donor HIV screening was performed using cost-utility analysis. The single factor sensitivity analysis was performed on parameters in the model. [Results] 3.09 QALYs were gained for each transfusion recipient prevented from HIV infection. During 2020-2023, donor HIV screening at Shenzhen Blood Center saved 506.76 QALYs, and each QALY saved 182 900 yuan. [Conclusion] From the perspective of long-term benefit of transfusion recipients, HIV screening of blood donors demonstrates high health and economic value. |
| format | Article |
| id | doaj-art-f04cfec4cb214860a72b3aa5ffe0620d |
| institution | Kabale University |
| issn | 1004-549X |
| language | zho |
| publishDate | 2025-07-01 |
| publisher | Institute of Blood Transfusion of Chinese Academy of Medical Sciences |
| record_format | Article |
| series | Zhongguo shuxue zazhi |
| spelling | doaj-art-f04cfec4cb214860a72b3aa5ffe0620d2025-08-20T03:56:32ZzhoInstitute of Blood Transfusion of Chinese Academy of Medical SciencesZhongguo shuxue zazhi1004-549X2025-07-0138795896310.13303/j.cjbt.issn.1004-549x.2025.07.0141004-549X(2025)7-0958-06Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov modelHUANG Liqin0WANG Lilin1WU Linfen2ZUO Jiahui3ZENG Jinfeng4Shenzhen Blood Centre, Shenzhen 518040, ChinaShenzhen Blood Centre, Shenzhen 518040, ChinaShenzhen Blood Centre, Shenzhen 518040, ChinaShenzhen Blood Centre, Shenzhen 518040, ChinaShenzhen Blood Centre, Shenzhen 518040, China[Objective] To develop a comprehensive health economics evaluation model for HIV blood screening using Markov modeling, so as to evaluate the quality-of-life adjustment years (QALYs) gained by transfusion recipients after implementation of blood HIV screening. [Methods] Shenzhen Blood Center was selected as the validation case for model development. Based on historical HIV screening data of Shenzhen Blood Center and published literature, the health economics evaluation of donor HIV screening was performed using cost-utility analysis. The single factor sensitivity analysis was performed on parameters in the model. [Results] 3.09 QALYs were gained for each transfusion recipient prevented from HIV infection. During 2020-2023, donor HIV screening at Shenzhen Blood Center saved 506.76 QALYs, and each QALY saved 182 900 yuan. [Conclusion] From the perspective of long-term benefit of transfusion recipients, HIV screening of blood donors demonstrates high health and economic value.https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.07.014&lang=enblood screeningblood donorhuman immunodeficiency virus (hiv)cost-utility analysis |
| spellingShingle | HUANG Liqin WANG Lilin WU Linfen ZUO Jiahui ZENG Jinfeng Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov model Zhongguo shuxue zazhi blood screening blood donor human immunodeficiency virus (hiv) cost-utility analysis |
| title | Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov model |
| title_full | Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov model |
| title_fullStr | Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov model |
| title_full_unstemmed | Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov model |
| title_short | Cost-utility analysis of HIV screening in blood donors using a decision-tree Markov model |
| title_sort | cost utility analysis of hiv screening in blood donors using a decision tree markov model |
| topic | blood screening blood donor human immunodeficiency virus (hiv) cost-utility analysis |
| url | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.07.014&lang=en |
| work_keys_str_mv | AT huangliqin costutilityanalysisofhivscreeninginblooddonorsusingadecisiontreemarkovmodel AT wanglilin costutilityanalysisofhivscreeninginblooddonorsusingadecisiontreemarkovmodel AT wulinfen costutilityanalysisofhivscreeninginblooddonorsusingadecisiontreemarkovmodel AT zuojiahui costutilityanalysisofhivscreeninginblooddonorsusingadecisiontreemarkovmodel AT zengjinfeng costutilityanalysisofhivscreeninginblooddonorsusingadecisiontreemarkovmodel |