Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study
Aim: New microtubule-targeting agents are needed to improve cancer treatment. The recent characterization of the anticancer alkaloid securinine as a tubulin-binding agent prompted us to explore the interaction of related monomeric and dimeric analogues with tubulin. The interaction between the α/β-t...
Saved in:
Main Authors: | Gérard Vergoten, Christian Bailly |
---|---|
Format: | Article |
Language: | English |
Published: |
Open Exploration
2024-05-01
|
Series: | Exploration of Drug Science |
Subjects: | |
Online Access: | https://www.explorationpub.com/uploads/Article/A100847/100847.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A systematic review of proaporphine alkaloids and a pharmacological update
by: Christian Bailly
Published: (2025-02-01) -
Virtual Screening, Toxicity Evaluation and Pharmacokinetics of Erythrina Alkaloids as Acetylcholinesterase Inhibitor Candidates from Natural Products
by: Permana A, et al.
Published: (2025-02-01) -
Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension
by: Heather L. Clark, et al.
Published: (2025-02-01) -
Exploring the interactions of rapamycin with target receptors in A549 cancer cells: insights from molecular docking analysis
by: Sanjeev K. Ganesh, et al.
Published: (2025-01-01) -
The predicted value for venous thromboembolism based on a modified model of caprini combined with fasting blood glucose and D-dimer: a retrospective study
by: Ping Wang, et al.
Published: (2025-02-01)