Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study
Aim: New microtubule-targeting agents are needed to improve cancer treatment. The recent characterization of the anticancer alkaloid securinine as a tubulin-binding agent prompted us to explore the interaction of related monomeric and dimeric analogues with tubulin. The interaction between the α/β-t...
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Main Authors: | Gérard Vergoten, Christian Bailly |
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Format: | Article |
Language: | English |
Published: |
Open Exploration
2024-05-01
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Series: | Exploration of Drug Science |
Subjects: | |
Online Access: | https://www.explorationpub.com/uploads/Article/A100847/100847.pdf |
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