Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case report
Abstract. Background. Estimated 4%–8% of pregnancies are complicated by asthma. Adequate management in this population is critical to minimize complications. Patients presenting with asthma exacerbation are typically managed with standard bronchodilators and systemic corticosteroids. However, additi...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Health/LWW
2024-09-01
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| Series: | Emergency and Critical Care Medicine |
| Online Access: | http://journals.lww.com/10.1097/EC9.0000000000000098 |
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| author | Melanie Johnson Malak Abbas Jaber Abdo Mansour Mansour Jessica Jones |
| author_facet | Melanie Johnson Malak Abbas Jaber Abdo Mansour Mansour Jessica Jones |
| author_sort | Melanie Johnson |
| collection | DOAJ |
| description | Abstract. Background. Estimated 4%–8% of pregnancies are complicated by asthma. Adequate management in this population is critical to minimize complications. Patients presenting with asthma exacerbation are typically managed with standard bronchodilators and systemic corticosteroids. However, additional agents may be used in patients with refractory asthma exacerbation. Ketamine has been used in refractory bronchospasm, although its efficacy in published literature is heterogeneous.
Case Presentation. We present a case of a pregnant patient with severe asthma exacerbation refractory to standard and salvage treatment who achieved termination of bronchospasm with ketamine infusion.
Conclusion. After receiving ketamine infusion for several days, the patient had improved air flow and achieved successful extubation, without experiencing rebound bronchospasm. Although this individual clinical case alone cannot change guidelines or directives to use in refractory asthma exacerbations, it offers a possible treatment option to patients and providers in unusually severe cases with extenuating risk factors. |
| format | Article |
| id | doaj-art-f00a67ddf3fa4eaaacccb56ba71c74c4 |
| institution | OA Journals |
| issn | 2097-0617 2693-860X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Wolters Kluwer Health/LWW |
| record_format | Article |
| series | Emergency and Critical Care Medicine |
| spelling | doaj-art-f00a67ddf3fa4eaaacccb56ba71c74c42025-08-20T01:54:16ZengWolters Kluwer Health/LWWEmergency and Critical Care Medicine2097-06172693-860X2024-09-014313013310.1097/EC9.0000000000000098202409000-00007Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case reportMelanie Johnson0Malak Abbas1Jaber Abdo2Mansour Mansour3Jessica Jones4a Pharmacy Department, Beaumont Health, Dearborn, MI, USAa Pharmacy Department, Beaumont Health, Dearborn, MI, USAb Emergency Center, Beaumont Health, Dearborn, MI, USA.b Emergency Center, Beaumont Health, Dearborn, MI, USA.a Pharmacy Department, Beaumont Health, Dearborn, MI, USAAbstract. Background. Estimated 4%–8% of pregnancies are complicated by asthma. Adequate management in this population is critical to minimize complications. Patients presenting with asthma exacerbation are typically managed with standard bronchodilators and systemic corticosteroids. However, additional agents may be used in patients with refractory asthma exacerbation. Ketamine has been used in refractory bronchospasm, although its efficacy in published literature is heterogeneous. Case Presentation. We present a case of a pregnant patient with severe asthma exacerbation refractory to standard and salvage treatment who achieved termination of bronchospasm with ketamine infusion. Conclusion. After receiving ketamine infusion for several days, the patient had improved air flow and achieved successful extubation, without experiencing rebound bronchospasm. Although this individual clinical case alone cannot change guidelines or directives to use in refractory asthma exacerbations, it offers a possible treatment option to patients and providers in unusually severe cases with extenuating risk factors.http://journals.lww.com/10.1097/EC9.0000000000000098 |
| spellingShingle | Melanie Johnson Malak Abbas Jaber Abdo Mansour Mansour Jessica Jones Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case report Emergency and Critical Care Medicine |
| title | Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case report |
| title_full | Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case report |
| title_fullStr | Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case report |
| title_full_unstemmed | Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case report |
| title_short | Use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm: a case report |
| title_sort | use of ketamine for severe asthma exacerbation in a pregnant patient with persistent bronchospasm a case report |
| url | http://journals.lww.com/10.1097/EC9.0000000000000098 |
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