Roxadustat attenuates brain injury in mice with heat stroke by regulating mitochondrial fission and fusion
Objective To explore the protective effect and underlying mechanism of roxadustat (FG-4592), hypoxia-inducible factor-α (HIF-α) prolyl hydroxylase inhibitor, on brain injury caused by heat stroke (HS). Methods A total of 140 male C57BL/6J mice (6~8 weeks old, weighing 18~22 g) were subjected, and 4...
Saved in:
| Main Authors: | 10.16016/j.2097-0927.202405009, HUANG Xueyan, SHEN Tingting |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Army Medical University
2024-10-01
|
| Series: | 陆军军医大学学报 |
| Subjects: | |
| Online Access: | https://aammt.tmmu.edu.cn/html/202405009.htm |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Issues on clinical application of hypoxia-inducible factor prolyl hydroxylase inhibitor Roxadustat
by: TU Yan, et al.
Published: (2020-01-01) -
A Case Report of Hypothyrotropin Hypothyroidism Caused by Roxadustat
by: YAN Xuelian, et al.
Published: (2025-03-01) -
Research advances of roxadustat in the treatment of various diseases
by: Tian Qian-qian, et al.
Published: (2022-07-01) -
Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress
by: Tingting Fang, et al.
Published: (2025-02-01) -
Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study
by: Emiko Otsuka, et al.
Published: (2024-12-01)