Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients

Aim. To study relation of the heart remodeling processes and endothelial dysfunction in patients with chronic heart failure (CHF).Material and methods. Totally, 103 patients studied with post infarction cardiosclerosis. All patients selected to 3 groups by functional class (FC): I group consisted of...

Full description

Saved in:
Bibliographic Details
Main Authors: Ch. A. Abdullaeva, U. K. Kamilova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2016-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/315
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849698813316431872
author Ch. A. Abdullaeva
U. K. Kamilova
author_facet Ch. A. Abdullaeva
U. K. Kamilova
author_sort Ch. A. Abdullaeva
collection DOAJ
description Aim. To study relation of the heart remodeling processes and endothelial dysfunction in patients with chronic heart failure (CHF).Material and methods. Totally, 103 patients studied with post infarction cardiosclerosis. All patients selected to 3 groups by functional class (FC): I group consisted of 28 patients with CHF I FC, II — 46 patients with II FC and III — 29 patients with III FC by NYHA. All patients underwent echocardiography, dopplerography of brachial artery.Results. Post infarction remodeling of the left ventricle (LV) led notonly to structural remodeling of LV, with chamber dilation, wallsthinning, contractility decrease, but to changes of LV geometry.Contractility decrease of LV myocardium followed by the disorderedendothelium-dependent vessel dilation, with increase of pulsative andresistive indexes, sensitivity decrease of brachial artery to the shifttension.Conclusion. In CHF patients the processes of heart remodeling followed by remodeling of vessels, showing functional and humoral parameters of endothelial dysfunction.
format Article
id doaj-art-eff77934c3af4e9c975dbd22444843de
institution DOAJ
issn 1728-8800
2619-0125
language Russian
publishDate 2016-02-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-eff77934c3af4e9c975dbd22444843de2025-08-20T03:18:48Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252016-02-01151161910.15829/1728-8800-2016-1-16-19295Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patientsCh. A. Abdullaeva0U. K. Kamilova1Tashkent Medical Academy. TashkentТашкентская медицинская академия. Ташкент; Республиканский специализиpованный научно-практический медицинский центp теpапии и медицинской реабилитации. ТашкентAim. To study relation of the heart remodeling processes and endothelial dysfunction in patients with chronic heart failure (CHF).Material and methods. Totally, 103 patients studied with post infarction cardiosclerosis. All patients selected to 3 groups by functional class (FC): I group consisted of 28 patients with CHF I FC, II — 46 patients with II FC and III — 29 patients with III FC by NYHA. All patients underwent echocardiography, dopplerography of brachial artery.Results. Post infarction remodeling of the left ventricle (LV) led notonly to structural remodeling of LV, with chamber dilation, wallsthinning, contractility decrease, but to changes of LV geometry.Contractility decrease of LV myocardium followed by the disorderedendothelium-dependent vessel dilation, with increase of pulsative andresistive indexes, sensitivity decrease of brachial artery to the shifttension.Conclusion. In CHF patients the processes of heart remodeling followed by remodeling of vessels, showing functional and humoral parameters of endothelial dysfunction.https://cardiovascular.elpub.ru/jour/article/view/315chronic heart failureheart remodelingendothelial dysfunction
spellingShingle Ch. A. Abdullaeva
U. K. Kamilova
Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients
Кардиоваскулярная терапия и профилактика
chronic heart failure
heart remodeling
endothelial dysfunction
title Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients
title_full Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients
title_fullStr Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients
title_full_unstemmed Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients
title_short Relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients
title_sort relation of the heart remodeling and endothelial dysfunction in chronic heart failure patients
topic chronic heart failure
heart remodeling
endothelial dysfunction
url https://cardiovascular.elpub.ru/jour/article/view/315
work_keys_str_mv AT chaabdullaeva relationoftheheartremodelingandendothelialdysfunctioninchronicheartfailurepatients
AT ukkamilova relationoftheheartremodelingandendothelialdysfunctioninchronicheartfailurepatients